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The program was designed using the principles of the self-determination theory of motivation and personality. Patients were instructed to eat an Esselstyn-compliant, whole-food plant-based diet consisting of vegetables, fruits, whole grains, and legumes. Of the 389 participants in the program from September 2018 to February 2020, average weight loss was 5.8 pounds (7.3 for those whose body mass index was &gt;30), average systolic blood pressure drop was 6.8 points (16.8 points for those with systolic blood pressure &gt;140), average drop in cholesterol was 26 points (44 points for those with a cholesterol &gt;200), average drop in low-density lipoprotein was 19 points (33 points for those with a low-density lipoprotein &gt;100), and average drop in fasting blood sugar was 5.1 points (28.4 points for those starting in the diabetic range); P value was &lt;.005 for fasting blood sugar and &lt;.001 for all other comparisons. A 15-day program that helps patients adopt an Esselstyn-style whole-food plant-based diet, through education, individualized medical feedback, social support, and facilitated small group work, rapidly improves health.<\/jats:p>","DOI":"10.1177\/15598276211006349","type":"journal-article","created":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T07:23:42Z","timestamp":1617866622000},"page":"374-381","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Jumpstarting Health With a 15-Day Whole-Food Plant-Based Program"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0876-9888","authenticated-orcid":false,"given":"Susan M.","family":"Friedman","sequence":"first","affiliation":[{"name":"University of Rochester School of Medicine and Dentistry, Rochester, New York"},{"name":"Rochester Lifestyle Medicine Institute, Rochester, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol Hee","family":"Barnett","sequence":"additional","affiliation":[{"name":"Rochester Lifestyle Medicine Institute, Rochester, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Franki","sequence":"additional","affiliation":[{"name":"Rochester Lifestyle Medicine Institute, Rochester, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Pollock","sequence":"additional","affiliation":[{"name":"Rochester Lifestyle Medicine Institute, Rochester, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth","family":"Garver","sequence":"additional","affiliation":[{"name":"Rochester Lifestyle Medicine Institute, Rochester, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ted D.","family":"Barnett","sequence":"additional","affiliation":[{"name":"Rochester Lifestyle Medicine Institute, Rochester, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,4,8]]},"reference":[{"key":"bibr1-15598276211006349","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2318-11-47"},{"key":"bibr2-15598276211006349","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61460-4"},{"key":"bibr3-15598276211006349","unstructured":"Centers for Disease Control and Prevention. 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