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This exploratory study aimed to estimate the daily time investment necessary to comply with evidence-based recommendations related to the core pillars of LM. An integrative mixed-methods approach was employed, combining narrative synthesis of guidelines and scientific literature with applied individual time estimations performed by the authors. Evidence-based minimum recommendations suggested a cumulative requirement of approximately 11.4 hours per day dedicated to healthy lifestyle behaviors. Personal estimations demonstrated substantial variability, ranging from 9.8 to 16.7 hours\/day. Importantly, the incorporation of \u201cinvisible time\u201d components, including preparation, commuting, hygiene, organization, and logistical demands, substantially increased the total temporal burden associated with lifestyle interventions, reaching up to 22.6 hours\/day. Findings suggest that time represents a central, yet underrecognized, structural determinant of adherence to LM recommendations and highlight the need for more realistic, integrated, and context-sensitive approaches to lifestyle prescription and implementation.<\/jats:p>","DOI":"10.1177\/15598276261484525","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T11:50:17Z","timestamp":1789127417000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["There Is No Pill for Time: The Missing Determinant of Lifestyle Medicine"],"prefix":"10.1177","author":[{"given":"Regina","family":"Chamon","sequence":"first","affiliation":[{"name":"S\u00e3o Jos\u00e9 dos Campos"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"La\u00edssa","family":"Margoni","sequence":"additional","affiliation":[{"name":"Independent Researcher, Balne\u00e1rio Cambori\u00fa, SC, Brazil (LM)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid Ardisson","family":"Colodete","sequence":"additional","affiliation":[{"name":"Independent Researcher, Vit\u00f3ria, ES, Brazil (IAC)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos W. 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