{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:02:49Z","timestamp":1791248569327,"version":"4.1.0"},"reference-count":38,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Food Nutr Bull"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Recent research has highlighted the influence of maternal factors on the health of the offspring. Intrauterine experiences may program metabolic, cardiovascular, and psychiatric disorders. We have shown that maternal vitamin B\n                      <jats:sub>12<\/jats:sub>\n                      status affects adiposity and insulin resistance in the child. Vitamin B\n                      <jats:sub>12<\/jats:sub>\n                      is important for brain development and function.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      We investigated the relationship between maternal plasma vitamin B\n                      <jats:sub>12<\/jats:sub>\n                      status during pregnancy and the child's cognitive function at 9 years of age.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We studied children born in the Pune Maternal Nutrition Study. Two groups of children were selected on the basis of maternal plasma vitamin B\n                      <jats:sub>12<\/jats:sub>\n                      concentration at 28 weeks of gestation: group 1 ( n = 49) included children of mothers with low plasma vitamin B\n                      <jats:sub>12<\/jats:sub>\n                      (lowest decile, &lt; 77 pM) and group 2 ( n = 59) children of mothers with high plasma vitamin B\n                      <jats:sub>12<\/jats:sub>\n                      (highest decile, &gt; 224 pM).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Children from group 1 performed more slowly than those from group 2 on the Color Trail A test (sustained attention, 182 vs. 159 seconds; p &lt; .05) and the Digit Span Backward test (short-term memory, p &lt;.05), after appropriate adjustment for confounders. There were no differences between group 1 and group 2 on other tests of cognitive function (intelligence, visual agnosia).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Maternal vitamin B\n                      <jats:sub>12<\/jats:sub>\n                      status in pregnancy influences cognitive function in offspring.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/156482650802900401","type":"journal-article","created":{"date-parts":[[2015,11,25]],"date-time":"2015-11-25T16:02:37Z","timestamp":1448467357000},"page":"249-254","source":"Crossref","is-referenced-by-count":116,"title":["Vitamin B\n                    <sub>12<\/sub>\n                    Status of Pregnant Indian Women and Cognitive Function in their 9-year-old Children"],"prefix":"10.1177","volume":"29","author":[{"given":"Vidya","family":"Bhate","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swapna","family":"Deshpande","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dattatray","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niranjan","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasika","family":"Ladkat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujala","family":"Watve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Fall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celeste A.","family":"de Jager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helga","family":"Refsum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chittaranjan","family":"Yajnik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2008,12,15]]},"reference":[{"key":"bibr1-156482650802900401","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/78.3.359"},{"key":"bibr2-156482650802900401","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199107000-00001"},{"key":"bibr3-156482650802900401","unstructured":"National Institutes of Health, Office of Dietary Supplements. Dietary supplement fact sheet: Vitamin B\n                      12\n                      . Available at: http:\/\/dietary-supplements.info.nih.gov\/factsheets\/vitaminb12.asp. 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