{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T12:57:47Z","timestamp":1777640267790,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Food Nutr Bull"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Folic acid fortification of cereal-grain products has markedly improved folate status and reduced the risks of neural tube defects and other chronic diseases in the populations participating in fortification programs. To more broadly extend its benefit to affected populations in developing countries, it would seem logical to incorporate folic acid fortification into existing or planned programs to minimize the incremental cost of this intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine the feasibility of providing folic acid through ongoing programs for salt iodization and vitamin A fortification of sugar.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Folic acid was added to iodized salt and vitamin A\u2013fortified sugar by various methods\u2014direct blending as a powder, spraying onto the carriers as aqueous solution or suspension, or blending as a micro-encapsulated premix. The multiple fortified samples were subjected to a prolonged storage stability test, and the retentions of the added micronutrients were followed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Folic acid was generally stable when incorporated into Guatemalan iodized salt and vitamin A\u2013fortified sugar. Even in the presence of encapsulated ferrous fumarate as an iron fortificant, samples retained &gt; 80% in salt and \u223c 70% in sugar samples respectively, after 9 months of storage at 40\u00b0C and 60% relative humidity. The addition of folic acid as a dry premix made by extrusion was most effective in retaining both folic acid and the other added micronutrients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The fortification method had a pronounced impact on the stability of both folic acid and the other added micronutrients. Proper encapsulation may be required to ensure the stability of multiple fortified foods.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/156482651103200104","type":"journal-article","created":{"date-parts":[[2015,11,25]],"date-time":"2015-11-25T15:46:12Z","timestamp":1448466372000},"page":"35-41","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Folic Acid Fortification through Existing Fortified Foods: Iodized Salt and Vitamin A\u2014Fortified Sugar"],"prefix":"10.1177","volume":"32","author":[{"given":"Yao Olive","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Levente L.","family":"Diosady","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annie S.","family":"Wesley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,3,10]]},"reference":[{"key":"bibr1-156482651103200104","doi-asserted-by":"publisher","DOI":"10.1016\/j.tifs.2005.03.012"},{"key":"bibr2-156482651103200104","doi-asserted-by":"publisher","DOI":"10.1006\/jfca.2002.1067"},{"key":"bibr3-156482651103200104","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8223(02)90281-6"},{"key":"bibr4-156482651103200104","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/130.2.129"},{"key":"bibr5-156482651103200104","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2621.2004.tb17889.x"},{"key":"bibr6-156482651103200104","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2621.2004.tb17887.x"},{"key":"bibr7-156482651103200104","first-page":"50","volume":"17","author":"Grosse SD","year":"2006","journal-title":"Agro Food Ind Hi Tech"},{"key":"bibr8-156482651103200104","volume-title":"WHO and FAO guidelines on food fortification with micronutrients, 2006","author":"Allen L","year":"2006"},{"key":"bibr9-156482651103200104","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfoodeng.2010.03.007"},{"key":"bibr10-156482651103200104","doi-asserted-by":"publisher","DOI":"10.1081\/SL-120003802"},{"key":"bibr11-156482651103200104","doi-asserted-by":"publisher","DOI":"10.1177\/156482650903000109"},{"key":"bibr12-156482651103200104","volume-title":"Method 33.149. Official methods of analysis","author":"Association of Official Analytical Chemists","year":"1984","edition":"14"},{"key":"bibr13-156482651103200104","doi-asserted-by":"publisher","DOI":"10.1177\/156482650202300209"},{"key":"bibr14-156482651103200104","doi-asserted-by":"crossref","unstructured":"Verlinde P, Albelda A Zulueta, Oey I, Temme E, Hendrickx M, Van Loey A. Nonenzymatic glycation reaction of folate with reducing sugars: a case study on [6S]-5-methyltetrahydrofolate and fructose. IUFoST World Congress\u201413th World Congress of Food Science and Technology, 2006. Available at http:\/\/www.inra.fr\/iufost2006\/iufost-2006-final-prog.pdf in page 46. Accessed on December 2, 2010.","DOI":"10.1051\/IUFoST:20060424"}],"container-title":["Food and Nutrition Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/156482651103200104","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/156482651103200104","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T06:16:19Z","timestamp":1777443379000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/156482651103200104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["10.1177\/156482651103200104"],"URL":"https:\/\/doi.org\/10.1177\/156482651103200104","relation":{},"ISSN":["0379-5721","1564-8265"],"issn-type":[{"value":"0379-5721","type":"print"},{"value":"1564-8265","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3]]}}}