{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:59:19Z","timestamp":1777730359254,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2018,11,4]],"date-time":"2018-11-04T00:00:00Z","timestamp":1541289600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Interv Neuroradiol"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Conventional intra-arterial digital subtraction angiography, which requires surgical exposure and ligation of the femoral or carotid artery, is a limited method of evaluating elastase-induced aneurysms in New Zealand white rabbits. The purpose of this study was to assess aneurysm morphology, occlusion rates and complications after flow diverter treatment comparing intravenous and intra-arterial digital subtraction angiography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We previously published a preclinical study in which we evaluated the occlusion rates of elastase-induced aneurysms after treatment with a prototype flow diverter, by using intra-arterial digital subtraction angiography at three months ( n\u2009=\u20099) and six months ( n\u2009=\u20099). In addition to that intravenous digital subtraction angiography before treatment, after one month (early follow-up group) and after three months (late follow-up group) was performed. Occlusion rates were compared within the two groups by means of residual contrast filling.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Baseline aneurysm characteristics revealed no significant differences between intra-arterial digital subtraction angiography and intravenous digital subtraction angiography. Aneurysm occlusion rates in both follow-up groups using intravenous digital subtraction angiography were significantly higher compared to intra-arterial digital subtraction angiography (early follow-up group: intravenous digital subtraction angiography (one month) versus intra-arterial digital subtraction angiography (three months); p\u2009=\u20090.03 and late follow-up group: intravenous digital subtraction angiography (three months) versus intra-arterial digital subtraction angiography (six months); p\u2009=\u20090.04). Intravenous digital subtraction angiography is feasible to detect and reproduce device occlusions, in-stent stenosis and post-stent stenosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Intravenous digital subtraction angiography can not give a sufficient statement on the aneurysm occlusion process compared to intra-arterial digital subtraction angiography and is therefore not recommended for imaging follow-up after flow diverter treatment in rabbits. Regarding untreated aneurysms and complications like device occlusions, in-stent stenosis and post-stent stenosis intravenous digital subtraction angiography proofed to be a good alternative to intra-arterial digital subtraction angiography in our study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1591019918808537","type":"journal-article","created":{"date-parts":[[2018,11,4]],"date-time":"2018-11-04T06:10:18Z","timestamp":1541311818000},"page":"157-163","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Intravenous versus intra-arterial digital subtraction angiography: Occlusion rate and complication assessment of experimental aneurysms after flow diverter treatment in rabbits"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0913-6740","authenticated-orcid":false,"given":"Andreas","family":"Simgen","sequence":"first","affiliation":[{"name":"Department of Neuroradiology, Saarland University Hospital, Homburg\/Saar, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiki","family":"Tomori","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Saarland University Hospital, Homburg\/Saar, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hagen","family":"Bomberg","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Saarland University Hospital, Homburg\/Saar, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umut","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Saarland University Hospital, Homburg\/Saar, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Roth","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Clinic Bremen-Mitte, Bremen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Reith","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Saarland University Hospital, Homburg\/Saar, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruben","family":"M\u00fchl-Bennighaus","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Saarland University Hospital, Homburg\/Saar, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,11,4]]},"reference":[{"key":"bibr1-1591019918808537","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.213.1.r99oc15223"},{"key":"bibr2-1591019918808537","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.106.479576"},{"key":"bibr3-1591019918808537","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1530"},{"key":"bibr4-1591019918808537","doi-asserted-by":"crossref","unstructured":"Simgen A, Ley D, Roth C, et\u00a0al. Evaluation of a newly designed flow diverter for the treatment of intracranial aneurysms in an elastase-induced aneurysm model, in New Zealand white rabbits.\n                      Neuroradiology.\n                      Epub ahead of print 14 November 2013. DOI: 10.1007\/s00234-013-1296-9.","DOI":"10.1007\/s00234-013-1296-9"},{"key":"bibr5-1591019918808537","doi-asserted-by":"crossref","unstructured":"Ley D, M\u00fchl-Benninghaus R, Yilmaz U, et\u00a0al\n                      .\n                      The Derivo embolization device, a second-generation flow diverter for the treatment of intracranial aneurysms, evaluated in an elastase-induced aneurysm model.\n                      Clin Neuroradiol.\n                      Epub ahead of print 23 December 2015. DOI: 10.1007\/s00062-015-0493-9.","DOI":"10.1007\/s00062-015-0493-9"},{"key":"bibr6-1591019918808537","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.533760"},{"key":"bibr7-1591019918808537","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.13120099"},{"key":"bibr8-1591019918808537","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2013.07.006"},{"key":"bibr9-1591019918808537","first-page":"1","volume":"22","author":"Fujiwara NH","year":"2001","journal-title":"AJNR Am J Neuroradiol"},{"key":"bibr10-1591019918808537","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-005-1425-1"},{"key":"bibr11-1591019918808537","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-016-1730-x"},{"key":"bibr12-1591019918808537","doi-asserted-by":"publisher","DOI":"10.15274\/INR-2014-10070"},{"key":"bibr13-1591019918808537","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2016.07.101"},{"key":"bibr14-1591019918808537","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4964"},{"key":"bibr15-1591019918808537","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A5010"},{"key":"bibr16-1591019918808537","doi-asserted-by":"crossref","unstructured":"Guzzardi G, Stanca C, Cerini P, et\u00a0al. Long-term follow-up in the endovascular treatment of intracranial aneurysms with flow-diverter stents: Update of a single-centre experience.\n                      Radiol Med.\n                      Epub ahead of print 30 January 2018. 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