{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T11:02:32Z","timestamp":1781521352995,"version":"3.54.1"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,7,7]],"date-time":"2020-07-07T00:00:00Z","timestamp":1594080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Interv Neuroradiol"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:p>\n                    Capillary malformation-arteriovenous malformation (CM-AVM) syndrome is a newly described entity characterized by autosomal dominantly inherited multifocal capillary malformations caused by\n                    <jats:italic toggle=\"yes\">RASA1<\/jats:italic>\n                    mutations (CM-AVM1) or\n                    <jats:italic toggle=\"yes\">EPHB4<\/jats:italic>\n                    mutations (CM-AVM2). Concurrent high-flow vascular anomalies in the brain are often present in the form of intracranial AVM or arteriovenous fistula (AVF). These high-flow lesions are often identified at or soon after birth because of the characteristic unique capillary malformations or a systemic disorder due to a high-flow shunt, such as respiratory distress or heart failure. However, de novo intracranial AVMs have not been reported in patients with CM-AVM syndrome. Herein, we report the case of a six-year-old boy with CM-AVM1 who had been treated for an intracranial pial arteriovenous fistula approximately five years previously, in whom a de novo intracranial AVM was identified on a follow-up angiographic study. To the best of our knowledge, this report is the first to document a de novo intracranial AVM in a patient with CM-AVM. We recommend careful neuroimaging follow-up even if initial neuroimaging screening is negative because of the risk of de novo AVM development.\n                  <\/jats:p>","DOI":"10.1177\/1591019920940515","type":"journal-article","created":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T01:09:27Z","timestamp":1594170567000},"page":"25-30","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["De novo intracranial arteriovenous malformation development after endovascular treatment for a pial arteriovenous fistula in capillary malformation-arteriovenous malformation syndrome"],"prefix":"10.1177","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0323-6628","authenticated-orcid":false,"given":"Bikei","family":"Ryu","sequence":"first","affiliation":[{"name":"Department of Neuroendovascular Therapy, St. Luke\u2019s International Hospital, Tokyo, Japan"},{"name":"Department of Neurosurgery, St. Luke\u2019s International Hospital, Tokyo, Japan"},{"name":"Department of Neurosurgery, Tokyo Women\u2019s Medical University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2911-6755","authenticated-orcid":false,"given":"Shinsuke","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Neuroendovascular Therapy, St. Luke\u2019s International Hospital, Tokyo, Japan"},{"name":"Department of Neurosurgery, St. Luke\u2019s International Hospital, Tokyo, Japan"},{"name":"Department of Neurosurgery, Tokyo Women\u2019s Medical University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuki","family":"Mochizuki","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, St. Luke\u2019s International Hospital, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuya","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, St. Luke\u2019s International Hospital, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshikazu","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, St. Luke\u2019s International Hospital, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasunari","family":"Niimi","sequence":"additional","affiliation":[{"name":"Department of Neuroendovascular Therapy, St. Luke\u2019s International Hospital, Tokyo, 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