{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T01:13:53Z","timestamp":1788225233174,"version":"build-2803163510"},"reference-count":42,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T00:00:00Z","timestamp":1609977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Interv Neuroradiol"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Prognostic factors for functional outcome after basilar artery occlusion (BAO) treated with modern endovascular therapy (EVT) are sparse. We investigated the association between clinical characteristics, readily available imaging variables, and outcome in BAO patients treated with EVT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective analysis from a large healthcare system\u2019s prospectively collected code stroke registry of acute BAO patients treated with EVT between January 2017\u2013January 2020. The primary outcome measure was a favorable 90-day modified Rankin score (mRS) of 0-2.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>65 patients (median age 67\u2009years, 57% male, median NIHSS 16) met the study inclusion criteria. Thrombolysis in Cerebral Infarction (TICI) 2\u2009b-3 revascularization was achieved in 57\/65 patients (88%) with a median time to revascularization of 445\u2009minutes [IQR 302-840]. Ninety-day good outcome was seen in 35% (23\/65) of patients. In a univariate analysis, age, history of ischemic stroke, baseline NIHSS, BAO site, and discharge mRS were associated with significant differences between the good and poor outcome groups. A multivariable logistic regression analysis demonstrated an independent association with 90-day good outcome and younger age (per 1-year, OR 0.79, 95% CI 0.64, 0.98) and good discharge mRS (0-2) (OR\u2009&gt;\u2009999.99, 95% CI 13.26,\u2009&gt;\u2009999.99).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients presenting with an acute BAO treated with modern EVT have a good 90-day outcome in over one-third of cases. Age and discharge mRS are independently associated with good 90-day outcome. Additional studies may focus on factors that can enhance discharge function after BAO, a novel prognostic indicator for favorable 90-day outcome in our study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1591019920987040","type":"journal-article","created":{"date-parts":[[2021,1,13]],"date-time":"2021-01-13T19:26:55Z","timestamp":1610566015000},"page":"531-538","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Age and discharge modified Rankin score are associated with 90-Day functional outcome after basilar artery occlusion treated with endovascular therapy"],"prefix":"10.1177","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2111-5523","authenticated-orcid":false,"given":"Rahul R","family":"Karamchandani","sequence":"first","affiliation":[{"name":"Neurology, Neurosciences Institute, Atrium Health, Charlotte, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dale","family":"Strong","sequence":"additional","affiliation":[{"name":"Information and Analytics Services, Atrium Health, Charlotte, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy B","family":"Rhoten","sequence":"additional","affiliation":[{"name":"Neurology, Neurosciences Institute, Atrium Health, Charlotte, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanushree","family":"Prasad","sequence":"additional","affiliation":[{"name":"Information and Analytics Services, Atrium Health, Charlotte, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"Selig","sequence":"additional","affiliation":[{"name":"Neurology, Neurosciences Institute, Atrium Health, Charlotte, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Defilipp","sequence":"additional","affiliation":[{"name":"Charlotte Radiology, Neurosciences Institute, Atrium Health, Charlotte, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6697-3724","authenticated-orcid":false,"given":"Andrew W","family":"Asimos","sequence":"additional","affiliation":[{"name":"Emergency Medicine, Neurosciences Institute, Atrium Health, Charlotte, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,1,7]]},"reference":[{"key":"bibr1-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70173-5"},{"key":"bibr2-1591019920987040","doi-asserted-by":"crossref","unstructured":"Mahmoudi M, Dargazanli C, Cagnazzo F, et al. Predictors of favorable outcome after endovascular thrombectomy in MRI: selected patients with acute basilar artery occlusion.\n                      AJNR Am J Neuroradiol\n                      2020; 41: 1670\u20131676.","DOI":"10.3174\/ajnr.A6741"},{"key":"bibr3-1591019920987040","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00923"},{"key":"bibr4-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.61.4.496"},{"key":"bibr5-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1002\/ana.23904"},{"key":"bibr6-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.59.4.567"},{"key":"bibr7-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00163-X"},{"key":"bibr8-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1713973"},{"key":"bibr9-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1706442"},{"key":"bibr10-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000202582.29510.6b"},{"key":"bibr11-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30395-3"},{"key":"bibr12-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2014-310250"},{"key":"bibr13-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2015-012089"},{"key":"bibr14-1591019920987040","doi-asserted-by":"crossref","unstructured":"Uno J, Kameda K, Otsuji R, et al. Mechanical thrombectomy for basilar artery occlusion compared with anterior circulation stroke.\n                      World Neurosurg\n                      2020; 134: e469\u2013e475.","DOI":"10.1016\/j.wneu.2019.10.097"},{"key":"bibr15-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.010840"},{"key":"bibr16-1591019920987040","doi-asserted-by":"crossref","unstructured":"Kang DH, Jung C, Yoon W, et al. Endovascular thrombectomy for acute basilar artery occlusion: a multicenter retrospective observational study.\n                      J Am Heart Assoc\n                      2018; 7: e009419.","DOI":"10.1161\/JAHA.118.009419"},{"key":"bibr17-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24336"},{"key":"bibr18-1591019920987040","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3870"},{"key":"bibr19-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2018.06.019"},{"key":"bibr20-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.118.023882"},{"key":"bibr21-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2018.04.022"},{"key":"bibr22-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.19.5.604"},{"key":"bibr23-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.8.3.383"},{"key":"bibr24-1591019920987040","doi-asserted-by":"publisher","DOI":"10.5811\/westjem.2019.12.45247"},{"key":"bibr25-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.511162"},{"key":"bibr26-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1177\/1747493016641951"},{"key":"bibr27-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1159\/000502083"},{"key":"bibr28-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2004.049924"},{"key":"bibr29-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1159\/000502084"},{"key":"bibr30-1591019920987040","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/ana.23906","volume":"74","author":"Menon BK","year":"2013","journal-title":"Ann Neurol"},{"key":"bibr31-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00762.2018"},{"key":"bibr32-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60690-0"},{"key":"bibr33-1591019920987040","author":"Powers WJ","year":"2019","journal-title":"Stroke"},{"key":"bibr34-1591019920987040","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00113"},{"key":"bibr35-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2020-323742"},{"key":"bibr36-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2020-324470"},{"key":"bibr37-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-009-5406-x"},{"key":"bibr38-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.622175"},{"key":"bibr39-1591019920987040","first-page":"1","volume":"28","author":"Caplan LR.","year":"1991","journal-title":"Clin Exp Neurol"},{"key":"bibr40-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.119.024889"},{"key":"bibr41-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1111\/jon.12130"},{"key":"bibr42-1591019920987040","doi-asserted-by":"publisher","DOI":"10.1177\/1747493017744465"}],"container-title":["Interventional Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1591019920987040","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1591019920987040","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1591019920987040","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:59:20Z","timestamp":1777460360000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1591019920987040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,7]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1177\/1591019920987040"],"URL":"https:\/\/doi.org\/10.1177\/1591019920987040","relation":{},"ISSN":["1591-0199","2385-2011"],"issn-type":[{"value":"1591-0199","type":"print"},{"value":"2385-2011","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,7]]}}}