{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T05:33:15Z","timestamp":1787895195884,"version":"build-2784847793"},"reference-count":36,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2022,11,10]],"date-time":"2022-11-10T00:00:00Z","timestamp":1668038400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Interv Neuroradiol"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The major mechanism of morbidity of delayed cerebral ischemia after subarachnoid hemorrhage (SAH) is considered to be severe vasospasm. Quantitative MRA (QMRA) provides direct measurements of vessel-specific volumetric blood flow and may permit a clinically relevant assessment of the risk of ischemia secondary to cerebral vasospasm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the utility of QMRA as an alternative imaging technique for the assessment of cerebral vasospasm after SAH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>QMRA volumetric flow rates of the anterior cerebral artery (ACA), middle cerebral artery (MCA), and posterior cerebral artery (PCA) were compared with vessel diameters on catheter-based angiography. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of QMRA for detecting cerebral vasospasm was determined by receiver-operating characteristic curves. Spearman correlation coefficients were calculated for QMRA flow versus angiographic vessel diameter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixty-six vessels (10 patients) were evaluated with QMRA and catheter-based angiography. The median percent QMRA flow of all vessels with angiographic vasospasm (55.0%, IQR 34.3\u201371.6%) was significantly lower than the median percent QMRA flow of vessels without vasospasm (91.4%, IQR 81.4\u2013100.4%) (p\u2009&lt;\u20090.001). Angiographic vasospasm reduced QMRA-assessed flow by 23\u2009\u00b1\u20095 (p\u2009=\u20090.018), 95\u2009\u00b1\u200912 (p\u2009=\u20090.042), and 16\u2009\u00b1\u20094 mL\/min (p\u2009=\u20090.153) in the ACA, MCA, and PCA, respectively, compared to vessels without angiographic vasospasm. The sensitivity, specificity, PPV, and NPV of QMRA for the discrimination of cerebral vasospasm was 84%, 72%, 84%, and 72%, respectively, for angiographic vasospasm &gt;25% and 91%, 60%, 87%, and 69%, respectively, for angiographic vasospasm &gt;50%. The Spearman correlation indicated a significant association between QMRA flows and vessel diameters ( r\n                      <jats:sub>s<\/jats:sub>\n                      \u2009=\u20090.71, p\u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Reduction in QMRA flow correlates with angiographic vessel narrowing and may be useful as a non-invasive imaging modality for the detection of cerebral vasospasm after SAH.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15910199221138167","type":"journal-article","created":{"date-parts":[[2022,11,10]],"date-time":"2022-11-10T23:39:01Z","timestamp":1668123541000},"page":"271-279","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Quantitative magnetic resonance angiography as an alternative imaging technique in the assessment of cerebral vasospasm after subarachnoid hemorrhage"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0896-2266","authenticated-orcid":false,"given":"Kevin A","family":"Shah","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Zucker School of Medicine at Hofstra\/Northwell, Hempstead, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3604-4334","authenticated-orcid":false,"given":"Timothy G","family":"White","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Zucker School of Medicine at Hofstra\/Northwell, Hempstead, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ina","family":"Teron","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Zucker School of Medicine at Hofstra\/Northwell, Hempstead, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3686-2695","authenticated-orcid":false,"given":"Justin","family":"Turpin","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Zucker School of Medicine at Hofstra\/Northwell, Hempstead, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir R","family":"Dehdashti","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Zucker School of Medicine at Hofstra\/Northwell, Hempstead, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard E","family":"Temes","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Zucker School of Medicine at Hofstra\/Northwell, Hempstead, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Black","sequence":"additional","affiliation":[{"name":"Department of Radiology, Zucker School of Medicine at Hofstra\/Northwell, Hempstead, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry H","family":"Woo","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Zucker School of Medicine at Hofstra\/Northwell, Hempstead, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,11,10]]},"reference":[{"key":"bibr1-15910199221138167","doi-asserted-by":"publisher","DOI":"10.1080\/02688699550041403"},{"key":"bibr2-15910199221138167","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.544700"},{"key":"bibr3-15910199221138167","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-018-3765-8"},{"key":"bibr4-15910199221138167","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-018-0572-2"},{"key":"bibr5-15910199221138167","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A6462"},{"key":"bibr6-15910199221138167","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeh205"},{"key":"bibr7-15910199221138167","doi-asserted-by":"publisher","DOI":"10.1016\/S0730-725X(00)00157-0"},{"key":"bibr8-15910199221138167","doi-asserted-by":"publisher","DOI":"10.1088\/0967-3334\/36\/7\/1517"},{"key":"bibr9-15910199221138167","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2010.12.079"},{"key":"bibr10-15910199221138167","doi-asserted-by":"crossref","unstructured":"Ducoffe A, Konstas A, Pile-Spellman J, et al. 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