{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T10:37:23Z","timestamp":1793356643888,"version":"4.5.0"},"reference-count":13,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,1,23]],"date-time":"2023-01-23T00:00:00Z","timestamp":1674432000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Interv Neuroradiol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Intracranial hemorrhage (ICH) secondary to hypertension (HTN) classically occurs in the basal ganglia, cerebellum, or pons. Vascular lesions such as aneurysms or arteriovenous malformations (AVMs) are more common in younger patients. We investigated the utility of diagnostic subtraction angiography (DSA) in young hypertensive patients with non-lobar ICH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective review (2013\u20132022) identified young (18\u201360 years) patients who underwent DSA for ICH. HTN history, ICH location, presence\/absence of subarachnoid hemorrhage (SAH), and computed tomography angiography (CTA) findings were collected. The main outcome was DSA-positivity, defined as presence of an AVM, aneurysm, Moyamoya disease, reversible cerebral vasoconstriction syndrome, or dural arteriovenous fistula on DSA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Two hundred sixty patients were included, and the DSA-positivity rate was 19%.<\/jats:p>\n                    <jats:p>\n                      DSA-positivity was lower in hypertensive patients with ICHs in the cerebellum, pons, or basal ganglia compared to the rest of the patient sample (9% vs 26%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0002, Fisher's exact test). We developed the ICH-Angio score (0\u20135 points) based on CTA findings, ICH location, HTN history, and presence of SAH to predict risk of underlying vascular lesions. DSA-positivity was lower in those with a score of 0 (0\/62; 0%) compared to a score of 1 (5\/52; 10%), 2 (17\/48; 35%), 3 (10\/20; 50%), 4 (5\/6; 83%), or 5 (3\/3; 100%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The ICH-Angio score was able to non-invasively rule out an underlying vascular etiology for ICH in up to one-third of patients. HTN, ICH location, CTA findings, and associated SAH can identify patients at low risk for harboring underlying vascular lesions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15910199231152505","type":"journal-article","created":{"date-parts":[[2023,1,24]],"date-time":"2023-01-24T00:27:55Z","timestamp":1674520075000},"page":"168-174","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Diagnostic yield of cerebral angiography for intracranial hemorrhage in young patients: A single-center retrospective analysis"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8451-7012","authenticated-orcid":false,"given":"Mohamed E","family":"El-Abtah","sequence":"first","affiliation":[{"name":"Case Western Reserve University School of Medicine, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Kashkoush","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Cleveland Clinic, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Achey","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Cleveland Clinic, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Patterson","sequence":"additional","affiliation":[{"name":"Cerebrovascular Center, Cleveland Clinic Foundation, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina Z","family":"Moore","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Cleveland Clinic, Cleveland, OH, USA"},{"name":"Cerebrovascular Center, Cleveland Clinic Foundation, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark D","family":"Bain","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Cleveland Clinic, Cleveland, OH, USA"},{"name":"Cerebrovascular Center, Cleveland Clinic Foundation, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,1,23]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.emc.2012.06.003"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nic.2010.07.003"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.21.2.209"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00593048"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.28.7.1406"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2007.11.008"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.572495"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.17.5.881"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100006533"},{"key":"e_1_3_2_11_2","article-title":"Reversible cerebral vasoconstriction syndrome: a common occurrence but rare diagnosis","volume":"12","author":"Grundt B","year":"2020","unstructured":"Grundt B, Bolling T, Ritch ML. Reversible cerebral vasoconstriction syndrome: a common occurrence but rare diagnosis. Cureus 2020; 12: e8546.","journal-title":"Cureus"},{"key":"e_1_3_2_12_2","first-page":"226","article-title":"Aneurysmal subarachnoid hemorrhage","volume":"114","author":"Petridis AK","year":"2017","unstructured":"Petridis AK, Kamp MA, Cornelius JF, et al. Aneurysmal subarachnoid hemorrhage. Dtsch Arztebl Int 2017; 114: 226\u2013236.","journal-title":"Dtsch Arztebl Int"},{"key":"e_1_3_2_13_2","first-page":"1254","article-title":"Differentiating reversible cerebral vasoconstriction syndrome with subarachnoid hemorrhage from other causes of subarachnoid hemorrhage","volume":"70","author":"Muehlschlegel S","year":"2013","unstructured":"Muehlschlegel S, Kursun O, Topcuoglu MA, et al. Differentiating reversible cerebral vasoconstriction syndrome with subarachnoid hemorrhage from other causes of subarachnoid hemorrhage. JAMA Neurol 2013; 70: 1254\u20131260.","journal-title":"JAMA Neurol"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2156"}],"container-title":["Interventional Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15910199231152505","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15910199231152505","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15910199231152505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:56:23Z","timestamp":1777460183000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15910199231152505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,23]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1177\/15910199231152505"],"URL":"https:\/\/doi.org\/10.1177\/15910199231152505","relation":{},"ISSN":["1591-0199","2385-2011"],"issn-type":[{"value":"1591-0199","type":"print"},{"value":"2385-2011","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,23]]}}}