{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:51:07Z","timestamp":1777729867536,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,8,13]],"date-time":"2023-08-13T00:00:00Z","timestamp":1691884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,8,13]],"date-time":"2023-08-13T00:00:00Z","timestamp":1691884800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Interv Neuroradiol"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Different combinations of medications are utilized during wrist access for radial artery (RA) or ulnar artery (UA) catheterization in neuroendovascular procedures to preclude vasospasm. These \u201ccocktails\u201d commonly include the calcium channel blocker Verapamil, without established benefit. We analyze outcomes in patients with and without Verapamil in their \u201ccocktail\u201d by using a case-control cohort of our single-center experience.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective log of consecutive patients who underwent diagnostic cerebral angiograms using RA\/UA access was retrospectively reviewed, and patients were grouped into Verapamil and non-Verapamil cohorts. The primary outcomes assessed were the presence of forearm skin rashes (hives) and RA\/UA spasms. Our initial management included Verapamil (5 mg) in the cocktail, but Verapamil was removed after we noticed the development of hives in multiple patients immediately following its injection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 221 patients underwent 241 RA\/UA diagnostic cerebral angiograms and were included in our analysis. One hundred and forty-nine patients (61.8%) underwent catheterization with Verapamil and 92 (38.2%) were catheterized without it. Four of the 149 patients in the Verapamil group (2.7%) developed hives during the procedure and were treated with Benadryl (25 mg). Of the 92 patients who did not receive Verapamil, there were zero (0%) cases of hives and one (1.1%) case of vasospasm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Verapamil in the \u201ccocktail\u201d for wrist access diagnostic cerebral angiograms was associated with periprocedural hives, but not associated with a significant reduction in spasm compared to the non-Verapamil group. Our findings suggest that the administration of prophylactic Verapamil for these procedures may not be necessary.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15910199231193932","type":"journal-article","created":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T01:25:16Z","timestamp":1691976316000},"page":"43-49","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The impact of Verapamil for radial access in diagnostic cerebrovascular angiograms: A retrospective case-control study"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0150-4174","authenticated-orcid":false,"given":"Dominic","family":"Romeo","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed M.","family":"Salem","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3937-4029","authenticated-orcid":false,"given":"Georgios S.","family":"Sioutas","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Corral Tarbay","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinggang Jenny","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pakinam E.","family":"Aboutaleb","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Visish M.","family":"Srinivasan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA"},{"name":"Department of Neuroradiology, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryan","family":"Pukenas","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian T.","family":"Jankowitz","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA"},{"name":"Department of Neuroradiology, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan-Karl","family":"Burkhardt","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA"},{"name":"Department of Neuroradiology, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,8,13]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2019-015127"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2021-017325"},{"key":"e_1_3_2_4_2","article-title":"Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in people with coronary artery disease. Cochrane Heart Group, ed","volume":"2018","author":"Kolkailah AA","year":"2018","unstructured":"Kolkailah AA, Alreshq RS, Muhammed AM, et al. Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in people with coronary artery disease. Cochrane Heart Group, ed. Cochrane Database Syst Rev 2018; 2018: 1\u201399.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60404-2"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.119.025811"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2022.02.026"},{"key":"e_1_3_2_8_2","first-page":"221","article-title":"Brewing the right cocktail for radial intervention","volume":"62","author":"Vuurmans T","year":"2010","unstructured":"Vuurmans T, Hilton D. Brewing the right cocktail for radial intervention. Indian Heart J 2010; 62: 221\u2013225.","journal-title":"Indian Heart J"},{"key":"e_1_3_2_9_2","first-page":"280","article-title":"Variations in the usage and composition of a radial cocktail during radial access coronary angiography procedures","volume":"104","author":"Pate G","year":"2011","unstructured":"Pate G, Broderick B. Variations in the usage and composition of a radial cocktail during radial access coronary angiography procedures. Ir Med J 2011; 104: 280\u2013281.","journal-title":"Ir Med J"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.09.060"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.009449"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.119.025811"},{"key":"e_1_3_2_14_2","first-page":"527","article-title":"Radial artery spasm during transradial coronary procedures","volume":"23","author":"Kristi\u0107 I","year":"2011","unstructured":"Kristi\u0107 I, Lukenda J. Radial artery spasm during transradial coronary procedures. J Invasive Cardiol 2011; 23: 527\u2013531.","journal-title":"J Invasive Cardiol"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV8I11A192"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(95)00920-5"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2010.07.013"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20434"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-726X(200003)49:3<253::AID-CCD5>3.0.CO;2-5"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.113.000588"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.5598-20"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000267319.18123.d3"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1515\/dmpt-2015-0041"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2014.08.009"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/joic.12000"},{"key":"e_1_3_2_26_2","article-title":"Incidence and predictors of radial artery spasm during transradial coronary angiography and intervention","volume":"123","author":"Jia D","year":"2010","unstructured":"Jia D, Zhou Y, Shi D, et al. Incidence and predictors of radial artery spasm during transradial coronary angiography and intervention. Chin Med J 2010; 123: 843\u2013847. https:\/\/journals.lww.com\/cmj\/Fulltext\/2010\/04010\/Incidence_and_predictors_of_radial_artery_spasm.15.aspx","journal-title":"Chin Med J"},{"key":"e_1_3_2_27_2","article-title":"Urticaria after lidocaine use for pecto-intercostal nerve block","volume":"15","author":"Ambai VT","year":"2023","unstructured":"Ambai VT, Atawala N, Kalava A. Urticaria after lidocaine use for pecto-intercostal nerve block. Cureus 2023; 15: e34834.","journal-title":"Cureus"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.carrev.2011.11.003"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2009.01.012"}],"container-title":["Interventional Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15910199231193932","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15910199231193932","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15910199231193932","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:56:41Z","timestamp":1777460201000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15910199231193932"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,13]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1177\/15910199231193932"],"URL":"https:\/\/doi.org\/10.1177\/15910199231193932","relation":{},"ISSN":["1591-0199","2385-2011"],"issn-type":[{"value":"1591-0199","type":"print"},{"value":"2385-2011","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,13]]}}}