{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T05:42:37Z","timestamp":1786167757083,"version":"build-2736575974"},"reference-count":20,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,4,23]],"date-time":"2024-04-23T00:00:00Z","timestamp":1713830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Interv Neuroradiol"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>First-line treatment for symptomatic intracranial atherosclerotic disease (ICAD) is medical management; however, interventional approaches are increasingly considered for refractory disease. The Resolute Onyx in TIA management (ROTIA) study is a post-market evaluation of the Resolute Onyx (R-Onyx) drug-eluting stent in the treatment of recurrent transient ischemic attacks (TIAs) due to refractory ICAD (off-label use).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a single-center, retrospective case series of consecutive patients who underwent angioplasty and stenting with R-Onyx for treatment of recurrent TIAs due to refractory ICAD from October 2019 to November 2022. Included patients were ages 22\u201380, had a baseline modified Rankin Scale of \u22642, and had recurrent TIAs attributed to intracranial artery stenosis &gt;70% despite maximal medical therapy. Primary outcomes of interest were peri-procedural complications (TIA, stroke, intracranial hemorrhage, mortality) up to 72\u2005h post-stenting and ischemic stroke up to 18 months post-stenting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty patients (mean age 66.84\u2009\u00b1\u200914; 25% female; 80% Hispanic) were included. A total of 21 stents were successfully deployed with no peri-procedural complications. There were no recurrent ischemic events at 30 days post-stenting. At 18 months post-stenting, there were no ischemic events and no patient exhibited in-stent restenosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ROTIA demonstrates the feasibility of using the Resolute Onyx drug-eluting stent for the management of TIAs due to refractory ICAD, with high technical success and low peri-procedural complications. Limitations include the retrospective and single-center nature of this study. Future prospective, multi-center, randomized trials with extended observation periods are needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15910199241249211","type":"journal-article","created":{"date-parts":[[2024,4,23]],"date-time":"2024-04-23T04:23:11Z","timestamp":1713846191000},"page":"1422-1426","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["The resolute Onyx in TIA management (ROTIA)"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7148-7616","authenticated-orcid":false,"given":"Ameer E","family":"Hassan","sequence":"first","affiliation":[{"name":"Valley Baptist Medical Center \u2013 Harlingen"},{"name":"University of Texas Rio Grande Valley"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3169-5752","authenticated-orcid":false,"given":"Ahmed M","family":"Shoman","sequence":"additional","affiliation":[{"name":"Valley Baptist Medical Center \u2013 Harlingen"},{"name":"Mansoura University Hospitals, Mansoura, Dakahlia, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Miller","sequence":"additional","affiliation":[{"name":"Valley Baptist Medical Center \u2013 Harlingen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0297-9385","authenticated-orcid":false,"given":"Abdulrahman Ibrahim","family":"Hagrass","sequence":"additional","affiliation":[{"name":"Al-Azhar University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6803-3771","authenticated-orcid":false,"given":"Sohum","family":"Desai","sequence":"additional","affiliation":[{"name":"Valley Baptist Medical Center \u2013 Harlingen"},{"name":"University of Texas Rio Grande Valley"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamzah","family":"Saei","sequence":"additional","affiliation":[{"name":"Valley Baptist Medical Center \u2013 Harlingen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5556-5699","authenticated-orcid":false,"given":"Wondwossen G","family":"Tekle","sequence":"additional","affiliation":[{"name":"Valley Baptist Medical Center \u2013 Harlingen"},{"name":"University of Texas Rio Grande Valley"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,4,23]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.030898"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1412981"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1802712"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(23)00067-4"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.1326"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(20)30079-X"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000375"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62038-3"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.033033"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.1693"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.1074228"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/23969873221099715"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.03.005"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1080\/17434440.2020.1736037"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2021-017818"},{"key":"e_1_3_3_17_2","first-page":"159101992210843","article-title":"The resolute Onyx drug eluting stent for neurointervention: a technical series","author":"White TG","year":"2022","unstructured":"White TG, Shah KA, Koul P, et al. 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