{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:52:11Z","timestamp":1777729931758,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T00:00:00Z","timestamp":1747785600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Interv Neuroradiol"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Facial arteriovenous malformations (AVMs) can pose a risk of hemorrhage, bone erosion, and cosmetic deformity. Our objective is to evaluate treatment strategies and outcomes of patients with AVMs of the mandible and maxilla at our institution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective, consecutive series of patients with AVMs involving the mandible, maxilla and adjacent tissues was identified. Endovascular treatments included trans-arterial, trans-venous and\/or direct venous access embolization. Staged procedures were performed until arteriovenous (AV) shunting was minimized or eliminated. Dental extraction was utilized in patients with residual AV shunting of an affected alveolar ridge with refractory bleeding and loose dentition. Follow-up angiography was evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nine patients presented with AVMs of the mandible or maxilla to our institution in 1993\u20132023 (6 females; age range 7\u201338 years). Seven patients presented with a history of hemorrhage: two spontaneously and five at the time of biopsy or dental extraction. Embolization was performed in eight patients. Angiographic closure of the AVM was achieved in five patients. Six patients underwent surgery for debridement, resection or dental extraction. One lesion had complete spontaneous regression. No further bleeding episodes occurred in all patients. Seven patients had follow-up angiography (range 1\u201317 years) which showed significantly decreased or no residual AV shunting in all patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Multidisciplinary treatment involving embolization and\/or surgery can be accomplished safely and effectively for high-flow AVMs of the mandible and maxilla. Embolization with focused surgery may be a reasonable algorithm of clinical care and can result in significant reduction or durable closure of these lesions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15910199251343000","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T19:09:06Z","timestamp":1747854546000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Interventional treatment strategies for arteriovenous malformations of the mandible and maxilla: 30-year institutional case series"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5857-5718","authenticated-orcid":false,"given":"Nanthiya","family":"Sujijantarat","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Mass General Brigham, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Varun","family":"Padmanaban","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Mass General Brigham, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna M","family":"Larson","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Mass General Brigham, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria J","family":"Troulis","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Mass General Brigham, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonard B","family":"Kaban","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Mass General Brigham, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugh D","family":"Curtin","sequence":"additional","affiliation":[{"name":"Department of Radiology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James D","family":"Rabinov","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Mass General Brigham, Harvard Medical School, Boston, MA, USA"},{"name":"Department of Radiology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA"},{"name":"Diagnostic Neuroradiology, Mass General Brigham, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,5,21]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(86)90109-6"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2011.03.013"},{"key":"e_1_3_3_4_2","article-title":"E-086 mandibular AVM diagnosis and curative treatment","volume":"8","author":"Yakes W","year":"2016","unstructured":"Yakes W. E-086 mandibular AVM diagnosis and curative treatment. J Neurointerv Surg 2016; 8: A87\u2013A88.","journal-title":"J Neurointerv Surg"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-5182(97)80080-7"},{"key":"e_1_3_3_6_2","first-page":"578","article-title":"Tasanen A and j\u00e4\u00e4skel\u00e4inen J. Fatality from central hemangioma of the mandible","volume":"37","author":"Lamberg MA","year":"1979","unstructured":"Lamberg MA. Tasanen A and j\u00e4\u00e4skel\u00e4inen J. Fatality from central hemangioma of the mandible. J Oral Surg 1979; 37: 578\u2013584.","journal-title":"J Oral Surg"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2010.09.013"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2007.12.033"},{"key":"e_1_3_3_9_2","first-page":"696","article-title":"Management of vascular malformations of the mandible and maxilla: review and report of two cases treated by embolization and surgical obliteration","volume":"28","author":"Hoey MF","year":"1970","unstructured":"Hoey MF, Courage GR, Newton TH, et al. Management of vascular malformations of the mandible and maxilla: review and report of two cases treated by embolization and surgical obliteration. J Oral Surg 1970; 28: 696\u2013706.","journal-title":"J Oral Surg"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/15910199050110S117"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2017.04.026"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.omsc.2015.05.001"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(99)70258-1"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199809010-00006"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-5182(98)80059-0"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1539"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2006.06.259"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000002489"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2009.04.088"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-68967-3"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(82)90092-1"},{"key":"e_1_3_3_22_2","article-title":"Massive maternal haemorrhage due to a mandibular arteriovenous malformation in a term pregnancy: a case report","volume":"34","author":"Ryan K","year":"2022","unstructured":"Ryan K, Laing-Aiken Z, Chatila H. Massive maternal haemorrhage due to a mandibular arteriovenous malformation in a term pregnancy: a case report. Case Rep Womens Health 2022; 34: e00418.","journal-title":"Case Rep Womens Health"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.12968\/denu.2017.44.5.444"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.14639\/0392-100X-1351"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11282-024-00762-6"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1177\/159101991201800107"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000005423"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200311000-00005"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-007-0261-2"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2014.04.017"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2011-010179"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.3171\/2011.2.JNS09830"}],"container-title":["Interventional Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15910199251343000","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15910199251343000","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15910199251343000","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:56:55Z","timestamp":1777460215000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15910199251343000"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,21]]},"references-count":31,"alternative-id":["10.1177\/15910199251343000"],"URL":"https:\/\/doi.org\/10.1177\/15910199251343000","relation":{},"ISSN":["1591-0199","2385-2011"],"issn-type":[{"value":"1591-0199","type":"print"},{"value":"2385-2011","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,21]]},"article-number":"15910199251343000"}}