{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:52:20Z","timestamp":1777729940967,"version":"3.51.4"},"reference-count":35,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:00:00Z","timestamp":1748822400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Interv Neuroradiol"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Therapeutic occlusion of major cerebral arteries is sometimes required in pediatric cerebrovascular conditions of the head and neck. However, this procedure carries a considerable risk of stroke and de novo intracranial aneurysm formation. This study aims to assess the long-term clinical and radiographic outcomes of therapeutic cerebral artery occlusion in a pediatric cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective review was conducted on pediatric patients who underwent endovascular therapeutic occlusion between January 2002 and June 2023. Clinical presentation, radiographic findings, management strategies, and follow-up data were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighteen children (male-to-female ratio: 2:1, mean age: 8.8 years) were included. Most cases (83%) were symptomatic at presentation. The diagnoses included aneurysm (44.4%), arterial dissection (22.2%), arteriovenous shunting (22.2%), and craniocervical neoplasm (11.1%). Eight patients underwent carotid circulation occlusion, and 10 underwent vertebrobasilar system occlusions; the majority (77.7%) were performed electively. Detachable coils were the primary devices used. Complete occlusion was observed in 89.9% of cases on immediate control angiography, and repeat embolization was performed in 2 cases. Perioperative ischemic strokes were observed in five cases: three asymptomatic and two with mild symptoms that completely resolved on follow-up. No new infarcts, transient ischemic attacks, de novo intracranial aneurysms, or mortality were observed over a mean clinical and radiographic follow-up duration of 6.9 years and 4 years, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Therapeutic occlusion of major cerebral arteries appears to be a safe and effective treatment in pediatric patients. Nevertheless, long-term follow-up is recommended due to the theoretical risk of de novo aneurysm formation over their lifespan.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15910199251345024","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T04:08:21Z","timestamp":1748837301000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Endovascular therapeutic occlusion of major cerebral arteries in children"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8455-637X","authenticated-orcid":false,"given":"Kittiphop","family":"Somboonnithiphol","sequence":"first","affiliation":[{"name":"Cerebrovascular Surgery and Interventions Center, Boston Children's Hospital, Boston, MA, USA"},{"name":"Department of Diagnostic and Therapeutic Radiology, Ramathibodi Hospital, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6343-6950","authenticated-orcid":false,"given":"Soliman","family":"Oushy","sequence":"additional","affiliation":[{"name":"Cerebrovascular Surgery and Interventions Center, Boston Children's Hospital, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3634-4692","authenticated-orcid":false,"given":"Alfred P","family":"See","sequence":"additional","affiliation":[{"name":"Cerebrovascular Surgery and Interventions Center, Boston Children's Hospital, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1793-3398","authenticated-orcid":false,"given":"Darren B","family":"Orbach","sequence":"additional","affiliation":[{"name":"Cerebrovascular Surgery and Interventions Center, Boston Children's Hospital, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,6,2]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnis.2009.000539"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-3019(84)90392-6"},{"key":"e_1_3_4_4_2","first-page":"253","article-title":"Aneurysms of the petrous portion of the internal carotid artery: results of treatment with endovascular or surgical occlusion","volume":"11","author":"Halbach VV","year":"1990","unstructured":"Halbach VV, Higashida RT, Hieshima GB, et al. 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