{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:09:47Z","timestamp":1790356187204,"version":"4.1.0"},"reference-count":15,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T00:00:00Z","timestamp":1752537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Interv Neuroradiol"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Venous sinus stenting (VSS) is a well-established treatment for medically refractory venopathic intracranial hypertension (VIH), with consistent improvements reported in symptoms such as headache, papilledema, and pulsatile tinnitus. Cognitive dysfunction, however, remains underexplored in terms of burden and response to surgical intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective, single-center study was performed of patients that underwent VSS for VIH. Symptom severity was assessed using the Cerebral Venous Disorder Symptom Severity (CVDSS) scale. Scores were collected pre-operatively and post-operatively at 2 weeks and 6 weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 50 consecutive patients with a mean age of 35.7 years underwent venous sinus stent placement for VIH and were included. VSS resulted in a reduction of the average pressure gradient from 15.0 to 2.8 mmHg. Baseline CVDSS cognitive dysfunction scores were rated as moderate or severe in 84% of patients. Sixty-four percent of patients had improvement in cognitive dysfunction between baseline and 6-week post-operatively (OR 5.1 (95% CI: 2.2, 11.6)), with only 38% reporting ongoing moderate or severe cognitive dysfunction after stenting. Global symptom severity also demonstrated improvement at 6 weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Self-reported cognitive dysfunction is highly prevalent and often severe in patients with VIH. VSS is associated with significant improvement in short-term cognitive dysfunction scores in addition to global symptom severity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15910199251357730","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T07:57:34Z","timestamp":1752566254000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Self-reported cognitive dysfunction improves following venous sinus stenting"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5385-3785","authenticated-orcid":false,"given":"Omar","family":"Ashraf","sequence":"first","affiliation":[{"name":"Department of Neurological Surgery, Wake Forest University, Winston-Salem, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Medina","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Wake Forest University, Winston-Salem, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Kittel","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Data Science, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molly","family":"Ehrig","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Data Science, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Siddiqui","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Canon Stroke and Vascular Research Center, SUNY University at Buffalo, Buffalo, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferdinand K","family":"Hui","sequence":"additional","affiliation":[{"name":"Division of Neurointerventional Surgery, The Neuroscience Institute, The Queen's Medical Center, Honolulu, HI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8979-1993","authenticated-orcid":false,"given":"Kyle M","family":"Fargen","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Wake Forest University, Winston-Salem, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,7,15]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1227\/neu.0000000000002718"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2018-014172"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2012-010468"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/140408"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2021-017361"},{"key":"e_1_3_3_7_2","first-page":"20250429","article-title":"Commentary on the river stent trial: venous sinus stenting is safe and effective and can be fully evaluated using noninvasive methods","author":"Amans MR","year":"2025","unstructured":"Amans MR, Levitt M, Hirsch JA, et al. Commentary on the river stent trial: venous sinus stenting is safe and effective and can be fully evaluated using noninvasive methods. J Neurointerv Surg 2025: 20250429.","journal-title":"J Neurointerv Surg"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnis-2024-022976"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2018-014042"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnis-2023-021336"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/19714009211026923"},{"key":"e_1_3_3_12_2","first-page":"20250127","article-title":"The correlation between intracranial pressure and venous sinus pressures changes after venous sinus stenting","author":"Iyer AM","year":"2025","unstructured":"Iyer AM, Midtlien JP, Kittel C, et al. The correlation between intracranial pressure and venous sinus pressures changes after venous sinus stenting. J Neurointerv Surg 2025: 20250127.","journal-title":"J Neurointerv Surg"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/13854046.2023.2249176"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2013-004376"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/braincomms\/fcab202"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1159\/000490578"}],"container-title":["Interventional Neuroradiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15910199251357730","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15910199251357730","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15910199251357730","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:57:07Z","timestamp":1777460227000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15910199251357730"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,15]]},"references-count":15,"alternative-id":["10.1177\/15910199251357730"],"URL":"https:\/\/doi.org\/10.1177\/15910199251357730","relation":{},"ISSN":["1591-0199","2385-2011"],"issn-type":[{"value":"1591-0199","type":"print"},{"value":"2385-2011","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,15]]},"article-number":"15910199251357730"}}