{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T15:46:59Z","timestamp":1783525619979,"version":"3.55.0"},"reference-count":27,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Interv Neuroradiol"],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Understanding of costs associated with different mechanical thrombectomy (MT) approaches lags behind procedural efficacy and safety considerations. This study evaluates cost-effectiveness of MT using Monopoint (Route 92 Medical, San Mateo, CA) as first-line approach compared to traditional contact aspiration (CA) and stentriever\/aspiration (SA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective analysis of consecutively treated ICA terminus or M1 occlusion patients across four high-volume stroke centers was conducted, categorized into Monopoint, CA, or SA groups. Direct device costs and total costs were obtained from institutional databases. Statistical analyses included mixed-effects linear regression and multivariable analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 148 patients undergoing MT (Monopoint: 74, CA: 32, SA: 42), device costs were lowest for the Monopoint group ($7836\u2009\u00b1\u20094570) vs. CA ($10,089\u2009\u00b1\u20096078, p\u2009&lt;\u20090.001) and SA ($19,069\u2009\u00b1\u20094730, p\u2009&lt;\u20090.001). Total costs followed a similar pattern (Monopoint: $27,089\u2009\u00b1\u200919,899, CA: $28,883\u2009\u00b1\u200914,161, p\u2009&lt;\u20090.001, SA: $63,327\u2009\u00b1\u200972,440, p\u2009&lt;\u20090.001). Monopoint demonstrated a higher final expanded Thrombolysis In Cerebral Infarction (eTICI) 2C\/3 reperfusion rate (85.1% vs. 62.5% for CA, 71.4% for SA, p\u2009&lt;\u20090.001) and fewer passes (1.8 vs. 2.0, p\u2009=\u20090.001). Technique crossover occurred less often with Monopoint compared to CA (6.8% vs. 34.4%, p\u2009&lt;\u20090.001), and similar to SA (7.1%, p\u2009=\u20090.937). Post-procedural subarachnoid hemorrhage was more common with CA (16.7%) or SA (6.3%) compared to Monopoint (1.3%, p\u2009=\u20090.003).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>First-line MT with Monopoint showed lower direct and total costs compared to CA and SA. Monopoint cost-effectiveness may be driven by fewer passes, decreased adjunctive device use, higher recanalization rates, fewer complications, and less post-MT hemorrhage, highlighting potential economic benefits of an optimized MT strategy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15910199251395338","type":"journal-article","created":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T18:17:32Z","timestamp":1763403452000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Cost-effectiveness of mechanical thrombectomy performed with the Monopoint reperfusion system compared to conventional contact aspiration and combined stentriever and aspiration"],"prefix":"10.1177","author":[{"given":"Fabio","family":"Settecase","sequence":"first","affiliation":[{"name":"California Pacific Medical Center"},{"name":"Mills-Peninsula Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaehyun","family":"Kim","sequence":"additional","affiliation":[{"name":"California Pacific Medical Center"},{"name":"Mills-Peninsula Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joey D","family":"English","sequence":"additional","affiliation":[{"name":"California Pacific Medical Center"},{"name":"Mills-Peninsula Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warren T","family":"Kim","sequence":"additional","affiliation":[{"name":"California Pacific Medical Center"},{"name":"Mills-Peninsula Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajkamal S","family":"Khangura","sequence":"additional","affiliation":[{"name":"Sutter Medical Center Sacramento"},{"name":"Sutter Roseville Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahram","family":"Varjavand","sequence":"additional","affiliation":[{"name":"Sutter Medical Center Sacramento"},{"name":"Sutter Roseville Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thymur A","family":"Chaudhry","sequence":"additional","affiliation":[{"name":"Sutter Medical Center Sacramento"},{"name":"Sutter Roseville Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7534-5842","authenticated-orcid":false,"given":"Matthew D","family":"Alexander","sequence":"additional","affiliation":[{"name":"Sutter Medical Center Sacramento"},{"name":"Sutter Roseville Medical Center"},{"name":"Department of Radiology &amp; Imaging Sciences, University of Utah, Salt Lake City, UT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,11,17]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001303"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2019.116643"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00163-X"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1706442"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1713973"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2213379"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2214403"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2013-010713"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/15910199221107438"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2017-013256"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2016-012838"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2021-018318"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2022-018806"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.5469\/neuroint.2022.00283"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/15910199231177754"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-019-1291-9"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2022.3285"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2014-011282"},{"key":"e_1_3_2_20_2","first-page":"1","article-title":"Mechanical thrombectomy in patients with acute ischemic stroke: a health technology assessment","volume":"16","author":"Health Quality Ontario","year":"2016","unstructured":"Health Quality Ontario. 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