{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T09:50:50Z","timestamp":1791021050029,"version":"4.1.0"},"reference-count":65,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2018,1,23]],"date-time":"2018-01-23T00:00:00Z","timestamp":1516665600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Serum uric acid level increases in many inflammatory conditions. Uric acid triggers the vascular inflammation and artery damage, which causes to an increased risk of endothelial dysfunction and atherosclerosis. It is not clear in the literature whether uric acid contributes to uveitis by similar mechanisms. We investigated whether uric acid level increases in Behcet\u2019s disease patients with thrombosis or anterior uveitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>We reviewed the medical records of 914 Behcet\u2019s disease. After screening for exclusion criteria, there were 50 Behcet\u2019s disease patients with thrombotic complication and as the control group 202 BD patients without any vascular complication were included to the study. In the Anterior uveitis group, there were 53 Behcet\u2019s disease patients. The Control group consisted of 39 Beh\u00e7et\u2019s disease patients without eye findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean uric acid value was 4.96\u2009\u00b1\u20091.06\u2009mg\/dl in Behcet\u2019s disease patients with thrombosis whereas 4.08\u2009\u00b1\u20090.94\u2009mg\/dl in controls, indicating a significant difference ( p\u2009&lt;\u20090.001). There was no significant difference between the mean ages of the patients in both groups. The mean age of the BD group without eye findings was 39.31\u2009\u00b1\u200910.47 years and that of the Behcet\u2019s disease with Anterior Uveitis group was 37.72\u2009\u00b1\u20099.65 years ( p\u2009=\u20090.453). The mean serum UA in the BD group without eye findings was 4.21\u2009\u00b1\u20091.21\u2009mg\/dl, while in the BD with Anterior Uveitis group it was 4.57\u2009\u00b1\u20091.37\u2009mg\/dl ( p\u2009=\u20090.201).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The extent of increase in uric acid level was greater in Behcet\u2019s disease patients that have a thrombotic complication compared to those without thrombotic complication. Uric acid seems to play a role in the pathogenesis of thrombosis. It is concluded that the elevation of serum uric acid level in patients with anterior uveitis with Behcet\u2019s disease is not statistically significant.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1708538117742831","type":"journal-article","created":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T09:56:28Z","timestamp":1516787788000},"page":"378-386","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Could be serum uric acid a risk factor for thrombosis and\/or uveitis in Behcet\u2019s disease?"],"prefix":"10.1177","volume":"26","author":[{"given":"Avc\u0131","family":"At\u0131l","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology, Kayseri Education and Research Hospital, Kayseri, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9220-194X","authenticated-orcid":false,"given":"Avc\u0131","family":"Deniz","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Kayseri Training and Research Hospital, Kayseri, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,1,23]]},"reference":[{"key":"bibr1-1708538117742831","volume-title":"MKSAP 15 medical knowledge self-assessment program: rheumatology","author":"Bolster MB.","year":"2009"},{"key":"bibr2-1708538117742831","first-page":"1152","volume":"105","author":"Beh\u00e7et H.","year":"1937","journal-title":"Dermatologische Wochenschrift, Hamburg"},{"key":"bibr3-1708538117742831","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-7-20"},{"key":"bibr4-1708538117742831","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-200301000-00006"},{"key":"bibr5-1708538117742831","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2006.02832.x"},{"key":"bibr6-1708538117742831","doi-asserted-by":"crossref","unstructured":"RJ, Johnson Kang Feig D, Kiylighn S, et\u00a0al.  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