{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:13:58Z","timestamp":1777943638114,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T00:00:00Z","timestamp":1542672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Medical Science and Technology Development Foundation, Nanjing Department of Health","award":["ZKX16033"],"award-info":[{"award-number":["ZKX16033"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare the therapeutic effects of ultrasound-guided and non-guided catheter-directed thrombolysis in the treatment of deep venous thrombosis of lower extremity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From August 2015 to April 2016, 60 patients with lower extremity deep venous thrombosis were randomly divided into two groups ( n\u2009=\u200930 for each) to receive catheter-directed thrombolysis. Group A was treated under the ultrasound guidance, while Group B was treated without guidance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Catheter-directed thrombolysis was successfully performed by only one intubate in Group A but by 5.9 intubates in Group B. It took 15.4\u2009\u00b1\u20093.2\u00a0min in Group A, significantly less than that in Group B (30.8\u2009\u00b1\u20096.6\u00a0min, p\u2009&lt;\u20090.05). The incidences of hematoma were also remarkably different between the two groups (3.33% vs. 26.67%, p\u2009=\u20090.026). No pseudoaneurysm or arteriovenous fistula was found in Group A, but there were two cases of pseudoaneurysm and two cases of arteriovenous fistula in Group B (both 6.67%, p\u2009=\u20090.492). The circumference differences of the affected limb between before and after thrombolysis were 49.47\u2009\u00b1\u20092.484\u00a0mm in Group A, significantly higher than that in Group B (28.40\u2009\u00b1\u20092.856\u00a0mm, p\u2009&lt;\u20090.001). After treatment, the venous unobstructed improvement rates and deep vein patency rate were both better than those in Group B (77\u2009+\u20092.603% vs. 57.23\u2009+\u20091.828% and 80% vs. 46.67%, respectively; p\u2009&lt;\u20090.001). There were only three cases of PTS in Group A (10%, 3\/30), but there were 11 cases in Group B (36.67%, 11\/30).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Ultrasound-guided catheter-directed thrombolysis has advantages, with improvement of venous patency and decrease of the incidence of PTS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1708538118814609","type":"journal-article","created":{"date-parts":[[2018,11,21]],"date-time":"2018-11-21T00:23:11Z","timestamp":1542759791000},"page":"277-283","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Comparison of clear effect and the complications, and short and mid-term effects between ultrasound-guided and non-guided catheter-directed thrombolysis in the treatment of deep venous thrombosis of lower extremity"],"prefix":"10.1177","volume":"27","author":[{"given":"Chengyan","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Surgical Ultrasound, The Affiliated Drum Tower Hospital to Medical School of Nanjing University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huawei","family":"Zhuo","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, The Affiliated Drum Tower Hospital to Medical School of Nanjing University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, The Affiliated Drum Tower Hospital to Medical School of Nanjing University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiwei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Surgical Ultrasound, The Affiliated Drum Tower Hospital to Medical School of Nanjing University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junlan","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Surgical Ultrasound, The Affiliated Drum Tower Hospital to Medical School of Nanjing University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0890-391X","authenticated-orcid":false,"given":"Feng","family":"Ran","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, The Affiliated Drum Tower Hospital to Medical School of Nanjing University, 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