{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:14:48Z","timestamp":1777943688668,"version":"3.51.4"},"reference-count":38,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The ankle\u2013brachial index is a noninvasive modality to evaluate atherosclerosis and is a predictive role for future cardiovascular events and mortality. However, few studies have evaluated its relation to long-term future ischemic stroke in hemodialysis patients. Therefore, we examined the relationship between ankle\u2013brachial index and ischemic stroke events among hemodialysis patients in a seven-year follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 84 patients were enrolled. Ankle\u2013brachial index was assessed in January 2009. Primary outcomes included ischemic stroke. An ankle\u2013brachial index\u2009&lt;\u20090.9 was considered abnormal and 1.4\u2009\u2265\u2009ankle\u2013brachial index\u2009\u2265\u20090.9 to be normal ankle\u2013brachial index.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean values for ankle\u2013brachial index were 0.98\u2009\u00b1\u20090.21at study entrance. In addition, 28 patients encountered ischemic stroke in the seven-year follow-up. In univariate Cox regression analysis, old age (hazard ratio (HR): 1.065, 95% confidence interval (CI): 1.030\u20131.102, p\u2009&lt;\u20090.001), low seven-year averaged serum phosphate levels (HR: 0.473, 95% CI: 0.306\u20130.730, p\u2009=\u20090.001), and abnormal ankle\u2013brachial index (HR: 0.035, 95% CI: 0.009\u20130.145, p\u2009&lt;\u20090.001) were risk factors for ischemic stroke. In multivariate Cox regression analysis for significant variables in univariate analysis, abnormal ankle\u2013brachial index (HR: 0.058, 95% CI: 0.012\u20130.279, p\u2009&lt;\u20090.001) and low seven-year averaged serum phosphate levels (HR: 0.625, 95% CI: 0.404\u20130.968, p\u2009=\u20090.035) remained the risk factors for ischemic stroke. The risk of ischemic stroke was 3.783-fold in patients with abnormal ankle\u2013brachial index compared with patients with normal ankle\u2013brachial index (HR: 3.783, 95% CI: 1.731\u20138.269, p\u2009=\u20090.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings suggest that ankle\u2013brachial index is an impressive predictor of future ischemic stroke among hemodialysis patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1708538120925954","type":"journal-article","created":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T02:26:41Z","timestamp":1593656801000},"page":"119-125","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Predictive value of ankle\u2013brachial index for long-term events of ischemic stroke in hemodialysis patients"],"prefix":"10.1177","volume":"29","author":[{"given":"Kai-Ni","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Nephrology, Tainan Sin-Lau Hospital, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Ping","family":"Chou","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tainan Sin-Lau Hospital, Tainan, Taiwan"},{"name":"Department of Health Care Administration, Chang Jung Christian University, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi-Chu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Health Care Administration, Chang Jung Christian University, Tainan, Taiwan"},{"name":"Department of Anesthesia, Tainan Sin-Lau Hospital, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsang-Shan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Tainan Sin-Lau Hospital, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric Kim-Tai","family":"Lui","sequence":"additional","affiliation":[{"name":"Faculty of Biochemistry, University of Toronto, Scarborough, Ontario, Canada, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih-Ho","family":"Chou","sequence":"additional","affiliation":[{"name":"Department of Neurology, Chi-Mei Medical Center, Tainan, Taiwan"},{"name":"Nan University of Pharmacy and Science, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1793-6377","authenticated-orcid":false,"given":"Chien-An","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Tainan Sin-Lau Hospital, Tainan, Taiwan"},{"name":"Department of Health Care Administration, Chang Jung Christian University, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,7,1]]},"reference":[{"key":"bibr1-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000088722.56342.A8"},{"key":"bibr2-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfq220"},{"key":"bibr3-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12281"},{"key":"bibr4-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1159\/000356086"},{"key":"bibr5-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfv009"},{"key":"bibr6-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.593442"},{"key":"bibr7-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.570903"},{"key":"bibr8-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-3848(01)00366-8"},{"key":"bibr9-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1159\/000267850"},{"key":"bibr10-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1159\/000075793"},{"key":"bibr11-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.16.1939"},{"key":"bibr12-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.19.3.538"},{"key":"bibr13-1708538120925954","doi-asserted-by":"crossref","first-page":"285","DOI":"10.7555\/JBR.30.2016K0006","volume":"30","author":"Lee HS","year":"2016","journal-title":"J Biomed Res"},{"key":"bibr14-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(01)00373-0"},{"key":"bibr15-1708538120925954","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.04101206"},{"key":"bibr16-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-011-0555-5"},{"key":"bibr17-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2005.06.016"},{"key":"bibr18-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2011.09.037"},{"key":"bibr19-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000065547.98258.3D"},{"key":"bibr20-1708538120925954","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.219046"},{"key":"bibr21-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.011321"},{"key":"bibr22-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-17-0663"},{"key":"bibr23-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.32.8.1721"},{"key":"bibr24-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1002\/clc.23188"},{"key":"bibr25-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0177609"},{"key":"bibr26-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1177\/0003319718814351"},{"key":"bibr27-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfv136"},{"key":"bibr28-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.009095"},{"key":"bibr29-1708538120925954","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01660309"},{"key":"bibr30-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.308"},{"key":"bibr31-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2010.02.013"},{"key":"bibr32-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0114678"},{"key":"bibr33-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-018-1578-y"},{"key":"bibr34-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.116.013195"},{"key":"bibr35-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.18.5.817"},{"key":"bibr36-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.14.12.1885"},{"key":"bibr37-1708538120925954","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.49.3434"},{"key":"bibr38-1708538120925954","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0b013e3181f7d043"}],"container-title":["Vascular"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1708538120925954","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1708538120925954","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1708538120925954","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:33:15Z","timestamp":1777707195000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1708538120925954"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,1]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1177\/1708538120925954"],"URL":"https:\/\/doi.org\/10.1177\/1708538120925954","relation":{},"ISSN":["1708-5381","1708-539X"],"issn-type":[{"value":"1708-5381","type":"print"},{"value":"1708-539X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,1]]}}}