{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T14:09:28Z","timestamp":1790431768019,"version":"4.1.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T00:00:00Z","timestamp":1595808000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Vascular access site complications after percutaneous transfemoral cardiovascular procedures remain a common cause of morbidity and mortality. We evaluated the SiteSeal\u00ae VCD for achieving hemostasis following diagnostic cardiac catheterization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a prospective case control single center study to assess the safety and efficacy of SiteSeal\u00ae VCD compared to standard manual compression following diagnostic cardiac catheterization. Forty patients were enrolled in study to receive either SiteSeal\u00ae device or manual compression (20 in each group).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Patients in the SiteSeal\u00ae group achieved hemostasis in a significantly shorter time (4\u2009\u00b1\u20092.4 vs. 19\u2009\u00b1\u20092.4\u2009min, P\u2009&lt;\u20090.001), had shorter time from hemostasis to ambulation (95\u2009\u00b1\u200944 vs. 388\u2009\u00b1\u200963\u2009min, P\u2009&lt;\u20090.001) and significantly earlier device deployment to discharge time compared to the manual compression group (4.7\u2009\u00b1\u20091.1 vs. 8.9\u2009\u00b1\u20094.8\u2009h, P\u2009=\u20090.001). There was one non-major bleeding event in the SiteSeal\u00ae group which occurred &gt;24\u2009h after discharge from the hospital and was managed conservatively. In the remaining device patients, there was no clinical or Doppler ultrasound evidence of major or minor vascular complication with good overall patient comfort at discharge, 7\u2009days and 30\u2009days follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this first clinical experience, the SiteSeal\u00ae VCD achieved safe and efficient hemostasis, allowed for earlier ambulation and faster discharge compared to manual compression.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1708538120934573","type":"journal-article","created":{"date-parts":[[2020,7,28]],"date-time":"2020-07-28T03:03:38Z","timestamp":1595905418000},"page":"228-236","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Safety and efficacy study of the wound care 360\u00b0 SiteSeal\u00ae vascular closure device in percutaneous cardiac catheterization procedures"],"prefix":"10.1177","volume":"29","author":[{"given":"Suresh","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Cardiovascular medicine, University of Kansas Medical Center and Hospital, Kansas City, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0799-1922","authenticated-orcid":false,"given":"Nilay","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular medicine, University of Kansas Medical Center and Hospital, Kansas City, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinodh","family":"Jeevanantham","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular medicine, University of Kansas Medical Center and Hospital, Kansas City, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamal","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular medicine, University of Kansas Medical Center and Hospital, Kansas City, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2373-1853","authenticated-orcid":false,"given":"Matthew B","family":"Earnest","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular medicine, University of Kansas Medical Center and Hospital, Kansas City, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,7,27]]},"reference":[{"key":"bibr1-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3181f9b345"},{"key":"bibr2-1708538120934573","doi-asserted-by":"publisher","DOI":"10.3109\/00016925309136722"},{"key":"bibr3-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.000536"},{"key":"bibr4-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.12.073"},{"key":"bibr5-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2013.03.011"},{"key":"bibr6-1708538120934573","first-page":"354","volume":"13","author":"Duffin DC","year":"2001","journal-title":"J Invasive Cardiol"},{"key":"bibr7-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21333"},{"key":"bibr8-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00101-9"},{"key":"bibr9-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1810340106"},{"key":"bibr10-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00970-3"},{"key":"bibr11-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00174-5"},{"key":"bibr12-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.10431"},{"key":"bibr13-1708538120934573","first-page":"251","volume":"15","author":"Nasu K","year":"2003","journal-title":"J Invasive Cardiol"},{"key":"bibr14-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)01081-X"},{"key":"bibr15-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01449-8"},{"key":"bibr16-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.10045"},{"key":"bibr17-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000079977.80153.80"},{"key":"bibr18-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000079982.80153.D9"},{"key":"bibr19-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.3.350"},{"key":"bibr20-1708538120934573","doi-asserted-by":"publisher","DOI":"10.4065\/80.8.1011"},{"key":"bibr21-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1016\/S1051-0443(96)70788-1"},{"key":"bibr22-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.10.032"},{"key":"bibr23-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1199"},{"key":"bibr24-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.06.048"},{"key":"bibr25-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20677"},{"key":"bibr26-1708538120934573","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2006.12.014"}],"container-title":["Vascular"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1708538120934573","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1708538120934573","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1708538120934573","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:33:23Z","timestamp":1777707203000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1708538120934573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,27]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1177\/1708538120934573"],"URL":"https:\/\/doi.org\/10.1177\/1708538120934573","relation":{},"ISSN":["1708-5381","1708-539X"],"issn-type":[{"value":"1708-5381","type":"print"},{"value":"1708-539X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,27]]}}}