{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T01:13:03Z","timestamp":1792458783109,"version":"4.5.0"},"reference-count":35,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,10,25]],"date-time":"2020-10-25T00:00:00Z","timestamp":1603584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Lower extremity amputation (LEA) is a major surgical procedure with a high risk of significant morbidity and mortality. The objective of this study was to describe mortality and functionality outcomes following this procedure in a developing country.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a retrospective study of all patients undergoing LEA for non-traumatic etiology between 2007 and 2017. Medical records were used to retrieve demographics, comorbidities, and perioperative complications of identified patients. Patients were contacted to follow-up on their medical, postoperative care, and ambulatory status. Mortality and postoperative functionality rates were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study included 78 patients. Median follow-up duration was 24\u2009months. Hypertension (81%) and diabetes (79%) were the most common comorbidities. Mortality rates at 30\u2009days, 1, and 5\u2009years were 10.3, 29.2, and 65.5%, respectively. Mortality was significantly associated with age\u2009&gt;\u200970 at amputation ( p\u2009=\u20090.042), hypertension ( p\u2009=\u20090.003), chronic kidney disease ( p\u2009=\u20090.031), and perioperative sepsis ( p\u2009=\u20090.01). Only 1.6% of patients were discharged into a specialized care center, and only 27% of patients were ambulatory postoperatively, although 90.5% were fitted with a prosthesis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Survival following major amputation in a developing country is currently comparable to more developed regions of the world. Major discrepancy seems to exist in ambulatory status following the procedure. Discharge placement policies should be properly set, and rehabilitation centers funding should be increased. Awareness may also be warranted to educate patients and families about the value and positive impact of rehabilitation centers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1708538120965081","type":"journal-article","created":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T01:43:46Z","timestamp":1603676626000},"page":"574-581","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Major lower extremity amputations in a developing country: 10-Year experience at a tertiary medical center"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8088-9801","authenticated-orcid":false,"given":"Mohamad A","family":"Chahrour","sequence":"first","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mouafak","family":"Homsi","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad R","family":"Wehbe","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Hmedeh","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamal J","family":"Hoballah","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2384-2633","authenticated-orcid":false,"given":"Fady F","family":"Haddad","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,10,25]]},"reference":[{"key":"bibr1-1708538120965081","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2013.06.055"},{"key":"bibr2-1708538120965081","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.08.983"},{"key":"bibr3-1708538120965081","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000470"},{"key":"bibr4-1708538120965081","first-page":"A141","volume":"8","author":"Peacock JM","year":"2011","journal-title":"Prev Chronic Dis"},{"key":"bibr5-1708538120965081","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.12.037"},{"key":"bibr6-1708538120965081","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2018.04.005"},{"key":"bibr7-1708538120965081","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-019-0353-8"},{"key":"bibr8-1708538120965081","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2007.11.005"},{"key":"bibr9-1708538120965081","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2016.12.015"},{"key":"bibr10-1708538120965081","first-page":"1303","volume":"21","author":"Meo SA","year":"2017","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"bibr11-1708538120965081","doi-asserted-by":"crossref","unstructured":"Aljarrah Q, Allouh MZ, Bakkar S, et al. 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