{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:22:39Z","timestamp":1791386559417,"version":"4.3.3"},"reference-count":42,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T00:00:00Z","timestamp":1611187200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare the safety and efficiency of atherectomy plus drug-coated balloon with drug-coated balloon only for the treatment of femoropopliteal artery lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This systematic review and meta-analysis was performed and reported following the requirement of the PRISMA. EMBASE, MEDLINE, and Cochrane library were queried from January 2000 to June 2020 to identify eligible literature. The modified Downs and Black checklist was used to assess the quality of included studies. Outcome measures included bail-out stenting, distal embolization, perforation, hematoma, primary patency at 12\u2009months, target lesion revascularization at 12\u2009months, leg amputation at 12\u2009months, and mortality at 12\u2009months. We used DerSimonian and Laird random-effects model to pool the dichotomous data on risk ratio (RR) with 95% confidence intervals (CIs) from each study to obtain an overall estimate for major outcomes. Subgroup analysis and sensitivity analyses were conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Six studies (two randomized controlled trials and four retrospective cohort studies) with 470 patients were included. Atherectomy plus drug-coated balloon group was associated with lower rates of bail-out stenting (RR: 0.49, 95%CI: 0.34\u20130.71, P\u2009&lt;\u20090.001). There was no significant difference between two groups in terms of distal embolization (RR: 2.06, 95%CI: 0.51\u20138.38, P\u2009=\u20090.31), perforation (RR: 2.04, 95%CI: 0.43\u20139.71, P\u2009=\u20090.37), hematoma (RR: 1.75, 95%CI: 0.43\u20137.09, P\u2009=\u20090.43), primary patency at 12\u2009months (1.09, 95%CI: 0.98\u20131.21, P\u2009=\u20090.12), target lesion revascularization at 12\u2009months (RR: 0.68, 95%CI: 0.41\u20131.14, P\u2009=\u20090.15), leg amputations at 12\u2009months (RR: 0.54, 95%CI: 0.13\u20132.23, P\u2009=\u20090.39), mortality at 12\u2009months (RR: 2.18, 95%CI: 0.71\u20136.64, P\u2009=\u20090.17). Sensitivity analysis had no effect on our findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The combination of atherectomy and drug-coated balloon was safe and effective in the treatment of femoropopliteal artery lesions, with lower incidence of bail-out stenting compared with drug-coated balloon only.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1708538120985732","type":"journal-article","created":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T00:53:16Z","timestamp":1611276796000},"page":"883-896","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["Atherectomy plus drug-coated balloon versus drug-coated balloon only for treatment of femoropopliteal artery lesions: A systematic review and meta-analysis"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1272-7755","authenticated-orcid":false,"given":"Feng","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoran","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjie","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7107-5892","authenticated-orcid":false,"given":"Zhigong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,1,21]]},"reference":[{"key":"bibr1-1708538120985732","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61249-0"},{"key":"bibr2-1708538120985732","first-page":"70","volume":"59","author":"Dessi K","year":"2018","journal-title":"J Cardiovasc 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