{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T21:27:27Z","timestamp":1781904447553,"version":"3.54.5"},"reference-count":17,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T00:00:00Z","timestamp":1619049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Venus ulcers developed mainly due to reflux of incompetent venous valves in perforating veins.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>In this randomized controlled trial, 119 patients recruited over two years, with post-phelebtic venous leg ulcers, were randomly assigned into one of two groups: either to receive radiofrequency ablation of markedly incompetent perforators (Group A, n\u2009=\u200962 patients) or to receive conventional compression therapy (Group B, n\u2009=\u200957 patients). Follow-up duration required for ulcer healing continued for 24\u2009months post randomization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Statistically significant shorter time to healing (ulcer complete healing or satisfactory clinical improvement) between both groups (56 patients, 90.3% of cases in Group A versus 44 patients 77.2% of cases in Group B) over the follow-up period of 24\u2009months was attained ( p \u2009=\u20090.001). Also, significantly different ulcer recurrence was recorded between both groups, 8 patients (12.9%) in Group A versus 19 patients (33.3%) in Group B ( p\u2009=\u20090.004).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In absence of deep venous obstruction, the monopolar radiofrequency ablation for incompetent perforators is a feasible and effective method that surpasses the traditional compression protocol for incompetent perforator-induced venous ulcers in terms of time required for healing even in the presence of unresolved deep venous valvular reflux.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17085381211010022","type":"journal-article","created":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T08:59:04Z","timestamp":1619081944000},"page":"357-364","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Radiofrequency ablation for markedly incompetent perforators versus compression therapy in the management of post-phelebtic venous ulcers: A randomized controlled trial"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5558-4133","authenticated-orcid":false,"given":"Mohamed Shukri","family":"Abdelgawad","sequence":"first","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Mansoura University Hospitals, Mansoura University, Mansoura, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amr M","family":"El-Shafei","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Mansoura University Hospitals, Mansoura University, Mansoura, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hesham A","family":"Sharaf El-Din","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Mansoura University Hospitals, Mansoura University, Mansoura, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehab M","family":"Saad","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Mansoura University Hospitals, Mansoura University, Mansoura, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamer A","family":"Khafagy","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Mansoura University Hospitals, Mansoura University, Mansoura, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amr","family":"Sameer","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Mansoura University Hospitals, Mansoura University, Mansoura, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nshaat A","family":"Elsaadany","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Mansoura University Hospitals, Mansoura University, Mansoura, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed A","family":"Abdelmaksoud","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, Mansoura University Hospitals, Mansoura University, Mansoura, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,4,22]]},"reference":[{"key":"bibr1-17085381211010022","first-page":"105","volume":"31","author":"Rabe 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