{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:26:35Z","timestamp":1793125595307,"version":"4.5.0"},"reference-count":38,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T00:00:00Z","timestamp":1629417600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this study is to investigate the potential association of the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with the primary patency of percutaneous transluminal angioplasty (PTA) in hemodialysis arteriovenous fistula (AVF) stenosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study conducted a retrospective review of patients with end-stage renal disease referred for hemodialysis AVF stenosis in one center. The study consisted of 114 patients with significant (significant stenosis was defined as a reduction in the caliber of the fistula vein of &gt; 50% with respect to the non-aneurysmal venous segment). AVF stenosis patients were treated with PTA, with conventional balloon angioplasty. The NLR and PLR were calculated from the pre-interventional blood samples. The patients were classified into two groups: group A, primary patency &lt; 12\u00a0months ( n = 35) and group B, and primary patency \u2265 12\u00a0months ( n = 79). Comparisons between the groups were performed using the Mann\u2013Whitney U test. Kaplan\u2013Meier analysis was performed to compare the factors, NLR and PLR, for association with primary patency AVFs. A receiver-operating characteristic curve analysis was performed to identify the sensitivity and specificity of the NLR and PLR cut-off values in the prediction of primary patency time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There was no difference in gender; age; side of AVF; AVF type; comorbid diseases such as diabetes mellitus and hypertension; or blood parameters such as white cell count, erythrocytes, hemoglobin, neutrophils, lymphocytes, monocytes, eosinophils, basophils, C-reactive protein, NLR, or PLR between the two groups ( p &gt; 0.05). There was also no significant difference in the patency rate between the NLR &lt; 4.13 and NLR \u2265 4.13 groups at 12\u00a0months (NLR cut-off point = 4.13, p = 0.273). There were statistically significant differences between the primary patency rates of the PLR &lt; 187.86 and PLR \u2265 187.86 groups at 12\u00a0months (PLR cut-off point = 187.86, p = 0.023). The cut-off value for PLR for the determination of primary patency was 187.86, with a sensitivity of 57.0% and specificity of 34.4%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>An increased level of PLR may be a risk factor for the development of early AVF restenosis after successful PTA. However, more studies are needed to validate this finding.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17085381211039672","type":"journal-article","created":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T03:53:43Z","timestamp":1629431623000},"page":"920-927","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Predictive value of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio for primary patency of percutaneous transluminal angioplasty in hemodialysis arteriovenous fistula stenosis"],"prefix":"10.1177","volume":"30","author":[{"given":"Feng","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbo","family":"Ci","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8084-0557","authenticated-orcid":false,"given":"Alimujiang","family":"Shawuti","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, People\u2019s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,8,20]]},"reference":[{"issue":"2","key":"bibr1-17085381211039672","first-page":"173","volume":"5","author":"Ghosh K","year":"2012","journal-title":"Int J Clin Exp 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