{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:16:51Z","timestamp":1777943811013,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T00:00:00Z","timestamp":1615939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Carbon dioxide angiography with addition of optical coherence tomography imaging may improve procedural success and clinical outcomes in patients with peripheral artery disease and chronic kidney disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Single-center, retrospective analysis of patients with chronic kidney disease who underwent carbon dioxide angiography and optical coherence tomography-guided chronic total occlusion crossing and\/or optical coherence tomography-guided directional atherectomy was performed. Patient and procedure-related characteristics, along with peri- and one-year post-procedural major adverse events, were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 18 vessels in 11 patients, with mean age 70\u2009years were treated. All had co-morbidities such as hypertension, hyperlipidemia, had history or were current smokers with baseline peripheral artery disease. Majority were diabetic with coronary disease (82%); 55% baseline chronic kidney disease IV, 55% Rutherford class III and 45% class IV. Contrast was used in only two patients. Mean total fluoroscopy time and radiation dose was 24.1\u2009min and 249.2 mGY, respectively. Half of the lesions were femoro-popliteal chronic total occlusions, and Ocelot catheter was used to cross seven of nine chronic total occlusions and was successful in six. Adjunctive optical coherence tomography-guided directional atherectomy was performed in 8 of 11 patients. Only two adverse events occurred: one clinically significant event of slow-flow intra-procedurally and one target limb revascularization within one year of index procedure in a vessel different than prior treated. Optical coherence tomography imaging in both chronic total occlusion-crossing and atherectomy resulted in 10-min mean fluoroscopy reduction time and 32 mGY reduction in radiation dose.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Carbon dioxide angiography with the addition of optical coherence tomography imaging for chronic total occlusion crossing and\/or optical coherence tomography-guided directional atherectomy reduced the need for contrast agents, total fluoroscopy time, and radiation exposure in patients with peripheral artery disease and baseline chronic kidney disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1708538121994373","type":"journal-article","created":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T02:34:42Z","timestamp":1616034882000},"page":"72-80","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Safety and outcomes of combined carbon dioxide angiography and OCT-guided femoro-popliteal chronic total occlusion crossing and directional atherectomy in patients with chronic kidney disease"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1087-4011","authenticated-orcid":false,"given":"Sehrish","family":"Memon","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Disease and Endovascular Medicine, Einstein Medical Center, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean","family":"Janzer","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Disease and Endovascular Medicine, Einstein Medical Center, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jon C","family":"George","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Disease and Endovascular Medicine, Einstein Medical Center, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,3,17]]},"reference":[{"key":"bibr1-1708538121994373","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000114519.75433.DD"},{"key":"bibr2-1708538121994373","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X09357230"},{"key":"bibr3-1708538121994373","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2002.34885"},{"key":"bibr4-1708538121994373","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2014.07.005"},{"key":"bibr5-1708538121994373","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2013.09.006"},{"key":"bibr6-1708538121994373","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01070905"},{"key":"bibr7-1708538121994373","doi-asserted-by":"publisher","DOI":"10.4103\/1995-705X.125926"},{"key":"bibr8-1708538121994373","doi-asserted-by":"publisher","DOI":"10.1177\/1179546819878680"},{"key":"bibr9-1708538121994373","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2017.03.446"},{"key":"bibr10-1708538121994373","unstructured":"Home. 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