{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:16:25Z","timestamp":1777943785174,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2022,4,30]],"date-time":"2022-04-30T00:00:00Z","timestamp":1651276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Acute peripheral arterial ischemia (APAI) is an acute ischemic condition that develops as a result of embolism or thrombosis, and its morbidity and mortality are still high today. The objective of this study is to determine the effect of preoperative Neutrophil-to-Lymphocyte ratio (NLR) on mortality in patients admitted with the diagnosis of APAI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>178 patients who were diagnosed with acute peripheral arterial occlusion and underwent emergency embolectomy were evaluated retrospectively over a 7-year period. Patient demographics, clinical history, risk factors, comorbidity, and hemogram sub-parameters were documented. The endpoint of the patients was determined as death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 178 patients were identified with a mean age 74.29\u00b114.71 (range 28\u2013111) years; among them, 105 (59%) were female. 18% patients (32\/178) died within 30 days. Lower extremity involvement was present in 124 (69.7%) of the patients. A statistically significant difference was found between the mortality rates and blood parameters of the patients included in the study in terms of white blood count C-reactive protein (CRP), and age among those with normal distribution. Neutrophil, NLR, procalcitonin, lactate, aspartate aminotransferase, and urea; It was statistically significant in terms of mortality in our patients with APAI. NLR values of the deceased were determined as 7.98 \u00b1 6.85.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>APAI patients with high NLRs had significantly higher risks of 30-day mortality. The NLR can be used as a prognostic marker in these patients and warrants further investigation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17085381221094943","type":"journal-article","created":{"date-parts":[[2022,4,30]],"date-time":"2022-04-30T04:58:06Z","timestamp":1651294686000},"page":"402-406","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of neutrophil-to-lymphocyte ratio with thirty-day mortality in acute peripheral arterial ischemia"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5072-8911","authenticated-orcid":false,"given":"Hatice","family":"Topcu","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Emergency Medicine Clinic, Health Science University, Sisli Hamidiye Etfal Training and Education Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helin","family":"El K\u0131l\u0131c","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Emergency Medicine Clinic, Health Science University, Sisli Hamidiye Etfal Training and Education Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,4,30]]},"reference":[{"key":"bibr1-17085381221094943","unstructured":"Robert B Rutherford. Vascular Surgery. 5th ed. Philedelphia: WB Saunders Company, 2000; pp. 822\u2013834."},{"issue":"4","key":"bibr2-17085381221094943","first-page":"319","volume":"7","author":"Keceligil HT","year":"1999","journal-title":"GKDC"},{"issue":"3","key":"bibr3-17085381221094943","first-page":"98","volume":"26","author":"Budak AB","year":"2017","journal-title":"Turkish J Vasc Surg"},{"issue":"1","key":"bibr4-17085381221094943","first-page":"6344","volume":"7","author":"Oz K","year":"2017","journal-title":"The Heart Surg Forum"},{"key":"bibr5-17085381221094943","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/2703518"},{"key":"bibr6-17085381221094943","doi-asserted-by":"publisher","DOI":"10.1586\/14779072.2016.1165091"},{"key":"bibr7-17085381221094943","doi-asserted-by":"publisher","DOI":"10.5551\/jat.9.219"},{"key":"bibr8-17085381221094943","doi-asserted-by":"publisher","DOI":"10.7150\/jca.23367"},{"key":"bibr9-17085381221094943","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2015(04)09"},{"key":"bibr10-17085381221094943","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0056745"},{"key":"bibr11-17085381221094943","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.03.067"},{"key":"bibr12-17085381221094943","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0252030"},{"key":"bibr13-17085381221094943","doi-asserted-by":"publisher","DOI":"10.1177\/1076029613475474"}],"container-title":["Vascular"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17085381221094943","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17085381221094943","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17085381221094943","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:36:57Z","timestamp":1777707417000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17085381221094943"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,30]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1177\/17085381221094943"],"URL":"https:\/\/doi.org\/10.1177\/17085381221094943","relation":{},"ISSN":["1708-5381","1708-539X"],"issn-type":[{"value":"1708-5381","type":"print"},{"value":"1708-539X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,30]]}}}