{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:16:31Z","timestamp":1777943791434,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T00:00:00Z","timestamp":1654128000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Transcarotid revascularization (TCAR) is a minimally invasive hybrid surgical carotid stenting technique which utilizes cerebral flow reversal as embolic protection during carotid lesion manipulation. This investigation was performed to define the perioperative risks associated with this operation in the obese patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A retrospective review of tandem carotid revascularization databases maintained at two high-volume health systems was performed to capture all TCARs performed between 2015 and 2022. A threshold of body mass index of 35\u00a0kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      defined the \u201cobese\u201d patient. Demographics, intraoperative, perioperative, and follow-up characteristics were compared using univariate analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We performed 793 TCAR procedures that qualified for study inclusion within the prespecified time. After applying our obesity definition, 129 patients qualified as obese and were compared to the remainder. There were no significant differences in baseline demographics as comparable Charlson Comorbidity Indices were noted between groups; however, obese patients had a significantly higher prevalence of hypertension, hyperlipidemia, and diabetes. Intraoperative, case complexity in the obese patients did not seem to be increased, as measured by operative time (68.4 \u00b1 23.0 vs 64.2 \u00b1 25.8\u00a0min, p = 0.09), fluoroscopic time (4.9 \u00b1 3.2 vs 4.6 \u00b1 3.6\u00a0min, p = 0.38), and estimated blood loss (40.6 \u00b1 49.0 vs 46.6 \u00b1 49.4\u00a0min, p = 0.22). Similarly, no disparities were observed with respect to ipsilateral stroke (3.1 vs. 1.7%, p = 0.29), contralateral stroke (0 vs. 0.2%, p &gt; 0.99), death (0 vs. 1.1%, p = 0.61), and stroke\/death (3.1 vs. 3.0%, p &gt; 0.99) in the 30-day perioperative period. Both cohorts were followed for approximately 1\u00a0year (12.0 \u00b1 13.4 vs 11.6 \u00b1 13.4\u00a0months, p = 0.76). During this period, rates of ipsilateral stroke (3.1% vs. 2.7%, p &gt; 0.99), contralateral stroke (1.1 vs. 0.8%, p &gt; 0.99), and death (4.7 vs. 6.2%, p = 0.68) were similar.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>TCAR performed in the obese population was not more challenging by intraoperative characteristics and did not result in a statistically higher incidence of adverse events in the perioperative phase.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17085381221106326","type":"journal-article","created":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T16:29:09Z","timestamp":1654187349000},"page":"1180-1186","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Transcarotid revascularization in obese patients"],"prefix":"10.1177","volume":"31","author":[{"given":"Hanaa","family":"Dakour-Aridi","sequence":"first","affiliation":[{"name":"Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleem K","family":"Mirza","sequence":"additional","affiliation":[{"name":"Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raghu L","family":"Motaganahalli","sequence":"additional","affiliation":[{"name":"Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherin E","family":"Leckie","sequence":"additional","affiliation":[{"name":"Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arash","family":"Keyhani","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kourosh","family":"Keyhani","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8962-9136","authenticated-orcid":false,"given":"S Keisin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,6,2]]},"reference":[{"key":"bibr1-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2015.04.460"},{"key":"bibr2-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000004496"},{"key":"bibr3-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.18441"},{"key":"bibr4-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2021.04.073"},{"key":"bibr5-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2021.05.046"},{"key":"bibr6-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2011.10.017"},{"key":"bibr7-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2008.05.012"},{"key":"bibr8-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003957"},{"key":"bibr9-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2018.07.005"},{"key":"bibr10-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.1427"},{"key":"bibr11-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0912321"},{"key":"bibr12-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"bibr13-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2016.05.092"},{"key":"bibr14-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.07.100"},{"key":"bibr15-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2011.11.135"},{"key":"bibr16-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2003.030486"},{"key":"bibr17-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.115.306883"},{"key":"bibr18-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.01.092"},{"key":"bibr19-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0801891"},{"key":"bibr20-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2018.10.053"},{"key":"bibr21-17085381221106326","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-018-0685-0"}],"container-title":["Vascular"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17085381221106326","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17085381221106326","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17085381221106326","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:37:15Z","timestamp":1777707435000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17085381221106326"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,2]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1177\/17085381221106326"],"URL":"https:\/\/doi.org\/10.1177\/17085381221106326","relation":{},"ISSN":["1708-5381","1708-539X"],"issn-type":[{"value":"1708-5381","type":"print"},{"value":"1708-539X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,2]]}}}