{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T12:59:37Z","timestamp":1793105977375,"version":"4.5.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2023,3,8]],"date-time":"2023-03-08T00:00:00Z","timestamp":1678233600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Half of those undergoing major lower limb amputation for peripheral arterial disease die within 1\u00a0year. Advance care planning reduces days in hospital and increases the chance of dying in a preferred place.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To investigate the prevalence and content of advance care planning for people having a lower limb amputation due to acute or chronic limb-threatening ischaemia or diabetes. Secondary aims were to explore its association with mortality, and length of hospital stay.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A retrospective observational cohort study. The intervention was advance care planning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting\/participants<\/jats:title>\n                    <jats:p>Patients admitted to the South West England Major Arterial Centre between 1 January 2019 and 1 January 2021 who received unilateral or bilateral below, above, or through knee amputation due to acute or chronic limb-threatening ischaemia or diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      116 patients were included in the study. 20.7% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 24) died within 1\u00a0year. 40.5% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 47) had an advance care planning discussion of which all included cardiopulmonary resuscitation decisions with few exploring other options. Patients who were more likely to have advance care planning discussions were \u226575\u00a0years (aOR = 5.58, 95%CI 1.56\u201320.0), female (aOR = 3.24, 95%CI 1.21\u20138.69), and had multimorbidity (Charlson Comorbidity Index \u22655, aOR = 2.97, 95%CI 1.11\u20137.92). Discussions occurred more often in the emergency pathway and were predominantly initiated by physicians. Advance care planning was associated with increased mortality (aHR = 2.63, 95%CI 1.01, 5.02) and longer hospital stay (aHR = 0.52, 95%CI 0.32\u20130.83).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Despite a high risk of death for all patients in the months following amputation, advance care planning occurred in fewer than half of people and mostly focused on resuscitation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17085381231162733","type":"journal-article","created":{"date-parts":[[2023,3,8]],"date-time":"2023-03-08T16:56:00Z","timestamp":1678294560000},"page":"824-833","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Amputation and advance care plans: An observational study exploring decision making and long-term outcomes in a vascular centre"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4437-3744","authenticated-orcid":false,"given":"Robert","family":"Grange","sequence":"first","affiliation":[{"name":"North Bristol NHS Trust"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Carter","sequence":"additional","affiliation":[{"name":"King\u2019s College London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Chamberlain","sequence":"additional","affiliation":[{"name":"Bristol Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Brooks","sequence":"additional","affiliation":[{"name":"North Bristol NHS Trust"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramya","family":"Nitharsan","sequence":"additional","affiliation":[{"name":"Cardiff Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Twine","sequence":"additional","affiliation":[{"name":"North Bristol NHS Trust"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Braude","sequence":"additional","affiliation":[{"name":"North Bristol NHS Trust"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,3,8]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.3402\/qhw.v11.32739"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.11367"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2016.12.015"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2016.12.331"},{"key":"e_1_3_4_6_2","unstructured":"End of life care for adults: service delivery NICE guideline [internet]. 2019 www.nice.org.uk\/guidance\/ng142."},{"key":"e_1_3_4_7_2","unstructured":"The World Health Organisation. 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