{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:18:44Z","timestamp":1788585524164,"version":"build-2803163510"},"reference-count":23,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T00:00:00Z","timestamp":1679270400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vascular"],"published-print":{"date-parts":[[2024,8]]},"abstract":"\n Background<\/jats:title>\n We investigated the role of obesity on morbidity and mortality in patients undergoing above knee amputation.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Data of 4225 patients undergoing AKAs was extracted from NIS Database (2016\u20132019) for a retrospectively matched case-control study and were grouped into; Non-obese (N-Ob-BMI <29.9\u00a0kg\/m\n 2<\/jats:sup>\n ;\n n<\/jats:italic>\n = 1413), class I\/II obese (Ob-I\/II-BMI: 30\u201339.9\u00a0kg\/m\n 2<\/jats:sup>\n ;\n n<\/jats:italic>\n = 1413), and class III obese groups (Ob-IIIBMI > 40;\n n<\/jats:italic>\n = 1399). Morbidity, mortality, length of stay, and hospital charges were analyzed.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Blood loss anemia (OR = 1.42; 95% CI = 1.19\u20131.64), superficial SSI (OR = 5.10; 95% CI = 1.4717.63) and acute kidney injury (AKI- OR = 1.42; 95% CI = 1.21\u20131.67) were higher in Ob-III patients. Mortality was 5.8%, 4.5%, and 6.4% in N-Ob, Ob-I\/II and Ob-III patients (\n p<\/jats:italic>\n < 0.001; Ob-I\/II vs. Ob-III), respectively. Hospital LOS was 3\u00a0days higher in Ob-III (16.1 \u00b1 18.0), comparatively resulting in $25,481 higher inpatient-hospital charge.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Patients in Ob-III group were noted to have increased morbidity, higher LOS, and inpatient-hospital cost.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/17085381231165592","type":"journal-article","created":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T08:54:01Z","timestamp":1679302441000},"page":"858-862","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Does obesity predict morbidity and mortality amongst patients undergoing transfemoral amputations?"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0903-152X","authenticated-orcid":false,"given":"Syed MMA","family":"Bokhari","sequence":"first","affiliation":[{"name":"VA North Texas Health Care System"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Senthil","family":"Sambandam","sequence":"additional","affiliation":[{"name":"VA North Texas Health Care System"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirling","family":"Tsai","sequence":"additional","affiliation":[{"name":"VA North Texas Health Care System"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishaal S","family":"Nathan","sequence":"additional","affiliation":[{"name":"VA North Texas Health Care System"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tejas","family":"Senthil","sequence":"additional","affiliation":[{"name":"VA North Texas Health Care System"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Lanier","sequence":"additional","affiliation":[{"name":"VA North Texas Health Care System"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Huerta","sequence":"additional","affiliation":[{"name":"VA North Texas Health Care System"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,3,20]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/00031348221074235"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.121.021456"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-020-05398-1"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.08.052"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10029021-02382-z"},{"issue":"5","key":"e_1_3_3_7_2","first-page":"138","article-title":"Obesity and diabetes","volume":"28","author":"Serv\u00e1n PR","year":"2013","unstructured":"Serv\u00e1n PR. 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Nutr Hosp 2013; 28(Supl 5): 138\u2013143.","journal-title":"Nutr Hosp"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2017.10.051"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1673352"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/NT.0000000000000092"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2006.01262.x"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.67.5.968"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020245"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa055643"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2014.02.003"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/s00029149(03)00031-6"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.1.55"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.10.007"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2012.11.005"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2008.02.014"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0950821x(05)80462-1"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.02.005"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10016-001-0337-8"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2011.301"}],"container-title":["Vascular"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17085381231165592","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17085381231165592","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17085381231165592","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:01:25Z","timestamp":1788584485000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17085381231165592"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,20]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1177\/17085381231165592"],"URL":"https:\/\/doi.org\/10.1177\/17085381231165592","relation":{},"ISSN":["1708-5381","1708-539X"],"issn-type":[{"value":"1708-5381","type":"print"},{"value":"1708-539X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,20]]}}}