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Severe skin reactions may restrict radiation delivery or limit further treatment. Acute radiation dermatitis (ARD) arises within three months of the initiation of RT and is characterized by erythema, desquamation, ulceration, and even necrosis. To prevent or manage ARD, multiple systemic and topical medications have been employed, including topical vitamins, metallic ointments, and dressings. Among them, dressings are widely used and competitive, as they provide an intact, moist environment to facilitate the re-epithelialization of impaired skin. Polyurethane film dressings (such as Mepitel film and Hydrofilm dressings) are guaranteed in preventing ARD, whereas foam dressings (such as Mepilex\u00ae Lite dressings) can effectively manage ARD. Hydrogels are the most promising material for radiation-induced wound dressings due to their biodegradability, porous structure, and delivery features. However, due to the complexity of the skin repair process and the uncertainty surrounding its underlying mechanisms, the wide clinical application of hydrogels in ARD still requires further investigation. This review discusses the classification and pathological processes of ARD, the types of dressings available for clinical use, and modern dressings used to prevent and treat ARD. The aim is to provide valuable insights for optimizing ARD prevention and management.\n                  <\/jats:p>","DOI":"10.1177\/17103568261415893","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T12:30:57Z","timestamp":1771331457000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Modern Dressings in the Prophylaxis and Management of Acute Radiation Dermatitis: A Narrative Review"],"prefix":"10.1177","author":[{"given":"Dandan","family":"Wang","sequence":"first","affiliation":[{"name":"From the,  Department of Oncology, Cancer Institute of Jiangsu University, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junjie","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Outpatient, Taihe Hospital, Hubei University of Medicine, Shiyan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yixin","family":"Cao","sequence":"additional","affiliation":[{"name":"From the,  Department of Oncology, Cancer Institute of Jiangsu University, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunpeng","family":"Yu","sequence":"additional","affiliation":[{"name":"From the,  Department of Oncology, Cancer Institute of Jiangsu University, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Litao","family":"Huang","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hezhong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, Taihe Hospital, Hubei University of Medicine, Shiyan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Taihe Hospital, Hubei University of Medicine, Shiyan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanliang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Oncology, Taihe Hospital, Hubei University of Medicine, Shiyan, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,2,17]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13897"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-016-0120-y"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.3747\/co.v17i4.493"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(00)00782-3"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.02.047"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-006-9480-9"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2013.07.047"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2022.1479"},{"issue":"6","key":"e_1_3_1_10_2","article-title":"Psychological stress affects the severity of radiation-induced acute skin reactions in breast cancer patients","volume":"26","author":"Sutherland AE","year":"2017","unstructured":"Sutherland AE, , Bennett NC, , Herst PM. 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