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There are strong indications that atopic patients, or at least those with a history of atopic dermatitis, have an increased risk of becoming sensitized to AGs. This results in higher prevalences of sensitization to AGs in pediatric populations. Female sex does not appear to be a risk factor. The sites most commonly affected by allergic contact dermatitis are the face (+\/\u2212 neck and scalp), hands, and \u201cgeneralized.\u201d Occupational allergic contact dermatitis from AGs does not occur frequently and usually manifests as hand dermatitis from shampoos (in hairdressers) and hand cleansers. Cosmetics are by far (&gt;80%) the most common products responsible for allergic reactions to AGs. Other culprit products include household and industrial cleansers, topical medications, wound foam dressings, and antiseptic products. Patch testing with commercial decyl glucoside (5% pet.) and lauryl glucoside (3% pet.) results not infrequently in dubious (?+) and irritant reactions. There are concerns that some weak \u201callergic\u201d reactions may actually be false-positive. Frequent coreactivity between AGs may be caused by cross-reactions, concomitant sensitization due to mixed alkyl chain compositions, common allergenic impurities, and overlapping composition of patch test materials. Cosmetics with the highest prevalences of one or more AGs are cleansing products for babies and children.<\/jats:p>","DOI":"10.1177\/17103568261464823","type":"journal-article","created":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T02:06:31Z","timestamp":1788573991000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Contact Allergy to Alkyl Glucosides: A Review. Part 2"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6666-7292","authenticated-orcid":false,"given":"Anton C.","family":"de Groot","sequence":"first","affiliation":[{"name":"From the \rDepartment of Dermato-Allergology and Occupational Dermatology, Amsterdam University Medical Center, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbertus A.","family":"Ipenburg","sequence":"additional","affiliation":[{"name":"From the \rDepartment of Dermato-Allergology and Occupational Dermatology, Amsterdam University Medical Center, Amsterdam, The Netherlands"},{"name":"Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Rustemeyer","sequence":"additional","affiliation":[{"name":"From the \rDepartment of Dermato-Allergology and Occupational Dermatology, Amsterdam University Medical Center, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,4]]},"reference":[{"key":"e_1_3_1_2_1","article-title":"Contact allergy to alkyl glucosides: A review. 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