{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T06:29:02Z","timestamp":1777789742348,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1986,9,1]],"date-time":"1986-09-01T00:00:00Z","timestamp":525916800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Biol Markers"],"published-print":{"date-parts":[[1986,9]]},"abstract":"<jats:p>\n                    We assayed prostatic specific antigen (PSA) and prostatic acid phosphatase (PAP) serum levels in 1305 subjects without malignant prostatic pathology by double antibody RIA I\n                    <jats:sup>125<\/jats:sup>\n                    to evaluate their specifity. When we set a second upper normal limit of 10 ng\/ml for PSA and 2.5 ng\/ml for PAP there was a significant increase of specificity. There were 2 and 3.7% false positive results in non-prostatic benign pathologies, 1.8 and 7.9% in non-prostatic malignant, 3.5 and 4.7% in non-complicated benign prostatic hypertrophy (BPH) and 3.3% for both in chronic prostatitis. In patients with complicated BPH and acute prostatitis the results were 64.8 and 24% for PSA and 20 and 16% for PAP. In conclusion, PSA is more specific than PAP in patients without acute inflammatory pathology of the prostate; the high rate of false positive values in the latter excludes its usefulness in these patients as diagnostic tumoral markers.\n                  <\/jats:p>","DOI":"10.1177\/172460088600100305","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T10:41:24Z","timestamp":1523875284000},"page":"141-146","source":"Crossref","is-referenced-by-count":15,"title":["Evaluation of Specific Antigen and Prostatic Acid Phosphatase Specificity. Study of False Values"],"prefix":"10.1177","volume":"1","author":[{"given":"Juan","family":"Morote","sequence":"first","affiliation":[{"name":"Services of Urology and Nuclear Medicine (Tumoral Markers Unit) C.S. Vall d'Hebron. Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alvaro","family":"Ruibal","sequence":"additional","affiliation":[{"name":"Services of Urology and Nuclear Medicine (Tumoral Markers Unit) C.S. Vall d'Hebron. Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Palou","sequence":"additional","affiliation":[{"name":"Services of Urology and Nuclear Medicine (Tumoral Markers Unit) C.S. Vall d'Hebron. Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1986,9,1]]},"reference":[{"key":"bibr1-172460088600100305","first-page":"159","volume":"17","author":"Wang M.C.","year":"1979","journal-title":"J Urol"},{"key":"bibr2-172460088600100305","first-page":"2428","volume":"40","author":"Papsidero L.D.","year":"1980","journal-title":"Cancer Res"},{"key":"bibr3-172460088600100305","first-page":"4658","volume":"40","author":"Kuriyama M.","year":"1980","journal-title":"Cancer Res"},{"key":"bibr4-172460088600100305","first-page":"37","volume":"66","author":"Papsidero L.D.","year":"1981","journal-title":"J Natl Cancer Inst"},{"key":"bibr5-172460088600100305","first-page":"3874","volume":"41","author":"Kuriyama M.","year":"1981","journal-title":"Cancer Res"},{"key":"bibr6-172460088600100305","doi-asserted-by":"publisher","DOI":"10.1159\/000225594"},{"key":"bibr7-172460088600100305","first-page":"3714","volume":"42","author":"Frankel A.E.","year":"1982","journal-title":"Cancer Res"},{"key":"bibr8-172460088600100305","first-page":"99","volume":"68","author":"Kuriyama M.","year":"1982","journal-title":"J Natl Cancer Inst"},{"key":"bibr9-172460088600100305","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)53431-X"},{"key":"bibr10-172460088600100305","first-page":"406","volume":"42","author":"Ban Y.","year":"1983","journal-title":"Fed Proc"},{"key":"bibr11-172460088600100305","first-page":"1253","volume":"29","author":"Killian C.S.","year":"1983","journal-title":"Clin Chem"},{"key":"bibr12-172460088600100305","first-page":"1057","volume":"30","author":"Seamonds B.","year":"1984","journal-title":"Clin Chem"},{"key":"bibr13-172460088600100305","first-page":"1057","volume":"30","author":"Yang N.","year":"1984","journal-title":"Clin Chem"},{"key":"bibr14-172460088600100305","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/30.5.649"},{"key":"bibr15-172460088600100305","first-page":"984","volume":"31","author":"Chen I.W.","year":"1985","journal-title":"Clin Chem"},{"key":"bibr16-172460088600100305","first-page":"984","volume":"31","author":"Loor R.","year":"1985","journal-title":"Clin Chem"},{"key":"bibr17-172460088600100305","author":"Rubial A.","year":"1985","journal-title":"Prostatic specific antigen (PSA) seric levels in patients having prostatic pathologies."},{"key":"bibr18-172460088600100305","author":"Morote J.","year":"1986","journal-title":"Usefulness of prostatic specific antigen dosifi-cation in human clinic."},{"key":"bibr19-172460088600100305","volume-title":"SPSSx User's guide.","author":"Noris M.J.","year":"1983"},{"key":"bibr20-172460088600100305","doi-asserted-by":"publisher","DOI":"10.1002\/jso.2930240219"},{"key":"bibr21-172460088600100305","first-page":"145","volume-title":"Congress of International Society of Urology","author":"Kuriyama M.","year":"1985"},{"key":"bibr22-172460088600100305","unstructured":"RuibalA., PortaF., PascualC. Determinati\u00f3n por RIA de la fosfatasa \u00e1cida prost\u00e1tica en patolog\u00edas no prost\u00e1ticas. Estudio de los falsos positivos. Ponencia al XLVI Congreso nacional de urologia, Jaca 1981; 151\u20137."},{"key":"bibr23-172460088600100305","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)53428-X"},{"key":"bibr24-172460088600100305","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910310204"},{"key":"bibr25-172460088600100305","first-page":"34","volume":"19","author":"Yam L.T.","year":"1981","journal-title":"Invest Urol"},{"key":"bibr26-172460088600100305","first-page":"1064","volume":"27","author":"Gorus F.K.","year":"1981","journal-title":"Clin Chem"}],"container-title":["The International Journal of Biological Markers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/172460088600100305","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/172460088600100305","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:57:54Z","timestamp":1777492674000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/172460088600100305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,9]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1986,9]]}},"alternative-id":["10.1177\/172460088600100305"],"URL":"https:\/\/doi.org\/10.1177\/172460088600100305","relation":{},"ISSN":["0393-6155","1724-6008"],"issn-type":[{"value":"0393-6155","type":"print"},{"value":"1724-6008","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,9]]}}}