{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T06:44:11Z","timestamp":1777790651497,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1990,10,1]],"date-time":"1990-10-01T00:00:00Z","timestamp":654739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Biol Markers"],"published-print":{"date-parts":[[1990,10]]},"abstract":"<jats:p>\n                    To evaluate the clinical usefulness of immunoscintigraphy with OC 125 in ovarian carcinoma, we studied 25 patients suspected of having ovarian carcinoma or in follow-up after surgery. Fourteen patients were studied with\n                    <jats:sup>131<\/jats:sup>\n                    I-OC 125 F(ab')2 and 11 with\n                    <jats:sup>111<\/jats:sup>\n                    In-OC 125 F(ab')2. No differences were observed with the use of either radionuclide.\n                  <\/jats:p>\n                  <jats:p>Global diagnostic indexes obtained were S = 100%, Sp = 44,5% and A = 81%. The low specificity obtained was remarkable: 5 false positive results in two uterine myomas, one abscess, one follicular cyst and one granulation tissue scar. On the other hand, all lesions of ovarian carcinoma were detected. Analysis of the evolution of tumor\/background (T\/B) uptake ratios from the first to the second day of exploration revealed a tendency for the ratio to diminish significantly (&gt; 15%) in false positive cases with the exception of the abscess while this did not happen in true positive cases, with the exception of a regional recurrence. Analysis of T\/B ratio variations could contribute towards elevating the test's specificity.<\/jats:p>","DOI":"10.1177\/172460089000500401","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T10:17:04Z","timestamp":1523873824000},"page":"159-165","source":"Crossref","is-referenced-by-count":2,"title":["Immunoscintigraphy with\n                    <sup>131<\/sup>\n                    I or\n                    <sup>111<\/sup>\n                    In Labelled OC 125 F(ab')2 Fragments in Patients with Ovarian Carcinoma"],"prefix":"10.1177","volume":"5","author":[{"given":"A.","family":"Jim\u00e9nez-Vicioso","sequence":"first","affiliation":[{"name":"Department of Radiology, Medical Schools Complutense, Madrid - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Torres","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Service, Hospital \u201cReina Sofia\u201d, Cordoba - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Jim\u00e9nez-Heffernan","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Service, Hospital \u201cReina Sofia\u201d, Cordoba - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.D.","family":"Grana","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Service, Hospital \u201cReina Sofia\u201d, Cordoba - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"Latre","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Service, Hospital \u201cReina Sofia\u201d, Cordoba - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"Llamas","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Service, Hospital \u201cReina Sofia\u201d, Cordoba - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.L.","family":"Carreras","sequence":"additional","affiliation":[{"name":"Department of Radiology, Medical Schools Complutense, Madrid - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mateo","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Service, Hospital \u201cReina Sofia\u201d, Cordoba - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1990,10,1]]},"reference":[{"key":"bibr1-172460089000500401","first-page":"167","volume":"25","author":"Biersack H.J.","year":"1986","journal-title":"J Nucl Med"},{"key":"bibr2-172460089000500401","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-70947-0_30"},{"key":"bibr3-172460089000500401","first-page":"307","volume":"25","author":"Chatal J.F.","year":"1984","journal-title":"J Nucl Med"},{"key":"bibr4-172460089000500401","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-70947-0_29"},{"key":"bibr5-172460089000500401","first-page":"1977","volume":"48","author":"Kalofonos H.P.","year":"1988","journal-title":"Cancer Res"},{"key":"bibr6-172460089000500401","first-page":"83","volume":"6","author":"Epenetos A.A.","year":"1982","journal-title":"The Lancet"},{"key":"bibr7-172460089000500401","doi-asserted-by":"publisher","DOI":"10.1097\/00006231-198408000-00002"},{"key":"bibr8-172460089000500401","first-page":"1369","volume":"26","author":"Pateisky N.","year":"1985","journal-title":"J Nucl Med"},{"key":"bibr9-172460089000500401","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(87)80340-X"},{"key":"bibr10-172460089000500401","first-page":"1807","volume":"28","author":"Chatal J.F.","year":"1987","journal-title":"J Nucl Med"},{"key":"bibr11-172460089000500401","doi-asserted-by":"publisher","DOI":"10.1007\/BF00253598"},{"key":"bibr12-172460089000500401","doi-asserted-by":"publisher","DOI":"10.1177\/172460088800300306"},{"key":"bibr13-172460089000500401","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(87)90254-X"},{"key":"bibr14-172460089000500401","first-page":"105","volume":"31","author":"Masi R.","year":"1987","journal-title":"J Nucl Med and Allied Sci"}],"container-title":["The International Journal of Biological Markers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/172460089000500401","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/172460089000500401","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:00:58Z","timestamp":1777492858000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/172460089000500401"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,10]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1990,10]]}},"alternative-id":["10.1177\/172460089000500401"],"URL":"https:\/\/doi.org\/10.1177\/172460089000500401","relation":{},"ISSN":["0393-6155","1724-6008"],"issn-type":[{"value":"0393-6155","type":"print"},{"value":"1724-6008","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,10]]}}}