{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T06:45:59Z","timestamp":1777790759914,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1992,10,1]],"date-time":"1992-10-01T00:00:00Z","timestamp":717897600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Biol Markers"],"published-print":{"date-parts":[[1992,10]]},"abstract":"<jats:p>\n                    Serum prolactin (PRL) concentrations at baseline and after TRH stimulation were determined in 15 healthy women and in 51 premenopausal patients suffering from Gross Cystic Breast Disease. All women were in the luteal phase of the menstrual cycle and patients were divided into three groups according to cyst type at presentation. Basal hormone levels were within the normal range in the control group and in the three cystic breast disease groups. The maximum PRL response to TRH stimulation was significantly higher (p &lt; 0.001) in patients with type I cysts (low Na\n                    <jats:sup>+<\/jats:sup>\n                    \/K\n                    <jats:sup>+<\/jats:sup>\n                    intracystic ratio and apocrine epithelium) than in patients with type II cysts (high Na\n                    <jats:sup>+<\/jats:sup>\n                    \/K\n                    <jats:sup>+<\/jats:sup>\n                    intracystic ratio and flattened epithelium), type III cysts (intermediate Na\n                    <jats:sup>+<\/jats:sup>\n                    \/K\n                    <jats:sup>+<\/jats:sup>\n                    intracystic ratio and mixed epithelium) and in normal women. Serum PRL concentrations corresponding to samples obtained 60 and 90 minutes after stimulation remained higher in the first group of patients. These results led us to consider the existence of an altered central regulation of PRL secretion in patients with type I cysts at presentation.\n                  <\/jats:p>","DOI":"10.1177\/172460089200700404","type":"journal-article","created":{"date-parts":[[2018,3,13]],"date-time":"2018-03-13T13:59:36Z","timestamp":1520949576000},"page":"225-229","source":"Crossref","is-referenced-by-count":2,"title":["Serum Prolactin Levels in Women with Gross Cystic Breast Disease"],"prefix":"10.1177","volume":"7","author":[{"given":"F.","family":"Vizoso","sequence":"first","affiliation":[{"name":"Surgery Service, Hospital de Jove, Gij\u00f3n"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.T.","family":"Allende","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, Hospital de Jove, Gij\u00f3n"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.L.","family":"Garc\u00eda-Mu\u00f1iz","sequence":"additional","affiliation":[{"name":"Surgery Services, Hospital Central de Asturias, Oviedo, and Department of Functional Biology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Alexandre","sequence":"additional","affiliation":[{"name":"Surgery Service, Hospital de Jove, Gij\u00f3n"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Fueyo","sequence":"additional","affiliation":[{"name":"Physiology Area, University of Oviedo, Oviedo - Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ruibal","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, Hospital de Jove, Gij\u00f3n"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1992,10,1]]},"reference":[{"key":"bibr1-172460089200700404","volume-title":"Breast carcinoma: risk and detection.","author":"Haagensen C.D.","year":"1981"},{"key":"bibr2-172460089200700404","first-page":"1","volume-title":"Endocrinology of cystic breast disease.","author":"Schwartz G.F.","year":"1983"},{"key":"bibr3-172460089200700404","first-page":"1055","volume":"61","author":"Page D.L.","year":"1978","journal-title":"J Natl Cancer Inst"},{"key":"bibr4-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1016\/0277-5379(85)90289-5"},{"key":"bibr5-172460089200700404","first-page":"209","volume":"16","author":"Vizoso F.","year":"1990","journal-title":"Eur J Surg Oncol"},{"key":"bibr6-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)92465-X"},{"key":"bibr7-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2964(77)90122-0"},{"key":"bibr8-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1019380"},{"key":"bibr9-172460089200700404","first-page":"360","volume":"1121","author":"Simkin B.","year":"1982","journal-title":"Proceedings of the 64th Annual Meeting of the Endocrine Society, San Francisco"},{"key":"bibr10-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1016\/0277-5379(84)90052-X"},{"key":"bibr11-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800651015"},{"key":"bibr12-172460089200700404","first-page":"121","volume":"84","author":"Gollinger R.C.","year":"1978","journal-title":"Surgery"},{"key":"bibr13-172460089200700404","first-page":"457","volume":"53","author":"Sitruk-Ware R.","year":"1979","journal-title":"Obstet Gynecol"},{"key":"bibr14-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19801015)46:8<1775::AID-CNCR2820460813>3.0.CO;2-7"},{"key":"bibr15-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)47479-0"},{"key":"bibr16-172460089200700404","first-page":"381","volume":"64","author":"Peters F.","year":"1984","journal-title":"Obstet Gynecol"},{"key":"bibr17-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19840315)53:6<1311::AID-CNCR2820530615>3.0.CO;2-R"},{"key":"bibr18-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19850801)56:3<500::AID-CNCR2820560315>3.0.CO;2-Z"},{"key":"bibr19-172460089200700404","volume-title":"Statistical principles in experimental design.","author":"Winer B.J.","year":"1971"},{"key":"bibr20-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-49-5-778"},{"key":"bibr21-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1987.60"},{"key":"bibr22-172460089200700404","first-page":"302","volume":"46","author":"Hagler L.","year":"1975","journal-title":"Obstet Gynecol"},{"key":"bibr23-172460089200700404","author":"Suarez B.","journal-title":"Int J Biol Markers"},{"key":"bibr24-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1177\/030089168206800506"},{"key":"bibr25-172460089200700404","doi-asserted-by":"publisher","DOI":"10.1016\/0039-128X(85)90082-0"},{"key":"bibr26-172460089200700404","first-page":"181","volume":"4","author":"Vizoso F.","year":"1989","journal-title":"Rev Clin Esp"},{"key":"bibr27-172460089200700404","first-page":"83","volume":"11","author":"Vizoso F.","year":"1990","journal-title":"Tumor Biology"}],"container-title":["The International Journal of Biological Markers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/172460089200700404","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/172460089200700404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:01:20Z","timestamp":1777492880000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/172460089200700404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,10]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1992,10]]}},"alternative-id":["10.1177\/172460089200700404"],"URL":"https:\/\/doi.org\/10.1177\/172460089200700404","relation":{},"ISSN":["0393-6155","1724-6008"],"issn-type":[{"value":"0393-6155","type":"print"},{"value":"1724-6008","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,10]]}}}