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In addition, dynamic serum determination of skeletal ALP could be a valid help in monitoring the efficacy of therapy in patients with bone progression.<\/jats:p>","DOI":"10.1177\/172460089501000108","type":"journal-article","created":{"date-parts":[[2018,3,13]],"date-time":"2018-03-13T13:58:23Z","timestamp":1520949503000},"page":"42-46","source":"Crossref","is-referenced-by-count":11,"title":["Skeletal alkaline phosphatase as a serum marker of bone metastases in the follow-up of patients with breast cancer"],"prefix":"10.1177","volume":"10","author":[{"given":"M.G.","family":"Reale","sequence":"first","affiliation":[{"name":"Department of Experimental Medicine, University \u201cLa Sapienza\u201d, Roma - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Santini","sequence":"additional","affiliation":[{"name":"Department of Experimental Medicine, University \u201cLa Sapienza\u201d, Roma - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.G.","family":"Marchei","sequence":"additional","affiliation":[{"name":"Department of Experimental Medicine, University \u201cLa Sapienza\u201d, Roma - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Manna","sequence":"additional","affiliation":[{"name":"Department of Experimental Medicine, University \u201cLa Sapienza\u201d, Roma - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Del Nero","sequence":"additional","affiliation":[{"name":"Department of Experimental Medicine, University \u201cLa Sapienza\u201d, Roma - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Bianco","sequence":"additional","affiliation":[{"name":"Department of Experimental Medicine, University \u201cLa Sapienza\u201d, Roma - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Marchei","sequence":"additional","affiliation":[{"name":"Department of Experimental Medicine, University \u201cLa Sapienza\u201d, Roma - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Frati","sequence":"additional","affiliation":[{"name":"Department of Experimental Medicine, University \u201cLa Sapienza\u201d, Roma - Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1995,1,1]]},"reference":[{"key":"bibr1-172460089501000108","volume-title":"The radio-immunochemical detection of cancer.","author":"Burchiel S.W.","year":"1982"},{"key":"bibr2-172460089501000108","volume-title":"Markers for diagnosis and monitoring of human cancer.","author":"Colnaghi M.I.","year":"1982"},{"key":"bibr3-172460089501000108","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1991.260"},{"key":"bibr4-172460089501000108","first-page":"2138","volume":"48","author":"Linsley P.S.","year":"1988","journal-title":"Cancer Res"},{"key":"bibr5-172460089501000108","doi-asserted-by":"publisher","DOI":"10.1016\/0277-5379(91)90468-S"},{"key":"bibr6-172460089501000108","first-page":"29","volume":"30","author":"Gion M.","year":"1986","journal-title":"J Nucl Med Allied Sci"},{"key":"bibr7-172460089501000108","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/39.1.131"},{"key":"bibr8-172460089501000108","first-page":"1105","volume":"9","author":"Desoize B.","year":"1989","journal-title":"Anti Cancer Research"},{"key":"bibr9-172460089501000108","first-page":"533","volume":"75","author":"Frenay M.","year":"1988","journal-title":"Bull Cancer (Paris)"},{"key":"bibr10-172460089501000108","first-page":"84","volume":"1","author":"Kamby C.","year":"1990","journal-title":"Value of serum (S)-osteocalcin determination. 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