{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:22:45Z","timestamp":1777944165397,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T00:00:00Z","timestamp":1458086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound"],"published-print":{"date-parts":[[2016,5]]},"abstract":"\n Background<\/jats:title>\n Transcranial Doppler ultrasound is used to screen and assess the intracranial arteries of children with sickle cell disease. Recent findings suggest that extracranial internal carotid artery (eICA) stenosis is also a contributing factor to silent cerebral infarction. Stenosis has been measured using phased array transducers with no beam\/flow angle correction and linear arrays with angle correction.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A total of 124 children undergoing TCD assessment were investigated for eICA velocities. Manual measurements of peak systolic velocity and TCD mean velocity were made with phased and linear array transducers.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Peak systolic velocities ranged from 60 to 534\u2009cm\/s (median 126\u2009cm\/s) using the linear array and 53 to 394\u2009cm\/s (median 115\u2009cm\/s) using the phased array transducers. TCD mean ranged from 39 to 419\u2009cm\/s (median 81\u2009cm\/s) using the linear array and 34 to 295\u2009cm\/s (median 72\u2009cm\/s) using the phased array transducers.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n There are advantages and disadvantages of each method, but stenoses were readily identified as focal velocity increases. We suggest thresholds for each transducer and recommend that imaging of the eICA forms part of screening for this group of children.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/1742271x16638891","type":"journal-article","created":{"date-parts":[[2016,3,17]],"date-time":"2016-03-17T20:28:49Z","timestamp":1458246529000},"page":"86-93","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Extracranial internal carotid artery stenosis in children with sickle cell disease \u2013 Which transducer, what measurement?"],"prefix":"10.1177","volume":"24","author":[{"given":"Colin R","family":"Deane","sequence":"first","affiliation":[{"name":"Department of Medical Engineering and Physics, King's College Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin J","family":"Freedman","sequence":"additional","affiliation":[{"name":"Department of Medical Engineering and Physics, King's College Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan E","family":"Height","sequence":"additional","affiliation":[{"name":"Department of Paediatric Haematology, King's College Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David C","family":"Rees","sequence":"additional","affiliation":[{"name":"Department of Paediatric Haematology, King's College Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,3,16]]},"reference":[{"key":"bibr1-1742271X16638891","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199807023390102"},{"key":"bibr2-1742271X16638891","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2010.022624"},{"key":"bibr3-1742271X16638891","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181ae2361"},{"key":"bibr4-1742271X16638891","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-014-2880-9"},{"key":"bibr5-1742271X16638891","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-09-599852"},{"key":"bibr6-1742271X16638891","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-69-818-172"},{"key":"bibr7-1742271X16638891","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2008.10.015"},{"key":"bibr8-1742271X16638891","doi-asserted-by":"publisher","DOI":"10.1053\/ejvs.2002.1621"},{"key":"bibr9-1742271X16638891","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1982.57.6.0769"}],"container-title":["Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1742271X16638891","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1742271X16638891","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1742271X16638891","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:47:59Z","timestamp":1777708079000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1742271X16638891"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,16]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["10.1177\/1742271X16638891"],"URL":"https:\/\/doi.org\/10.1177\/1742271x16638891","relation":{},"ISSN":["1742-271X","1743-1344"],"issn-type":[{"value":"1742-271X","type":"print"},{"value":"1743-1344","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,16]]}}}