{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:24:39Z","timestamp":1777944279394,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T00:00:00Z","timestamp":1718841600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The study aims to evaluate the role of the posterior hard palate angle in the prenatal diagnosis of cleft palate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design:<\/jats:title>\n                    <jats:p>Stored images of the axial transverse view of the fetal secondary palate, obtained at three-level obstetric ultrasounds, were used to evaluate the posterior border of the hard palate. The study population comprised 63 consecutive pregnancies of unaffected cases and 17 pregnancies suspected for a cleft palate without cleft lip, including 7 cases of cleft palate, 4 cases of high-arched palate, and 6 false-positive cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The posterior angle of the hard palate was significantly larger in the cleft palate group than in the healthy controls and false-positive cases: 227\u00b0 (\u00b151\u00b0) vs 160\u00b0 (\u00b116\u00b0), p &lt; 0.0001; and 173\u00b0 \u00b1 18\u00b0, p &lt; 0.0001, respectively. Regression analysis revealed that reflex angle remained an independent risk factor for cleft palate (odds ratio, 58.67 (95% confidence interval 10\u2013341)). The sensitivity and specificity of the posterior angle assessment were 73% and 96%, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The posterior hard palate angle could be an ultrasound marker of cleft palate without a cleft lip.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1742271x241260220","type":"journal-article","created":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T01:55:01Z","timestamp":1718934901000},"page":"12-18","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Diagnosis of fetal isolated cleft palate using assessment of the posterior hard palate angle"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5972-8272","authenticated-orcid":false,"given":"Iglika Ivancheva","family":"Simeonova-Brachot","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, University Hospital of Poitiers, Poitiers, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,6,20]]},"reference":[{"key":"bibr1-1742271X241260220","unstructured":"EUROCAT website database. 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