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Six databases were searched according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standards, in addition to the bibliography index listed in the CANTAB site. Twenty four studies regarding Down syndrome and 17 regarding prematurity were reviewed and are here described. Both cognitive profiles were described, and their performance was compared on specific tasks and CANTAB tests. In this battery of tests, people with Down syndrome usually present impaired key cognitive domains, such as episodic memory and recognition memory. Results were presented considering general aspects described in the studies, specific findings such as dementia, the role of genetics, and cognitive profile, among other descriptions. Comparability between both populations in future studies is discussed.<\/jats:p>","DOI":"10.1177\/17446295211050460","type":"journal-article","created":{"date-parts":[[2022,2,15]],"date-time":"2022-02-15T09:26:40Z","timestamp":1644917200000},"page":"539-567","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["The use of the cambridge neuropsychological test automated battery for people born with Down syndrome and those born premature: A comparative systematic review"],"prefix":"10.1177","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1751-8506","authenticated-orcid":false,"given":"Rosana M","family":"Trist\u00e3o","sequence":"first","affiliation":[{"name":"Faculty of Medicine and University Hospital, Medicine of the Child and Adolescent, University of Brasilia, Brasilia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9394-2272","authenticated-orcid":false,"given":"Lucas A","family":"Scafutto Marengo","sequence":"additional","affiliation":[{"name":"Psychology Institute, University of Brasilia, Brasilia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4487-1591","authenticated-orcid":false,"given":"Julia Feminella Duarte da","family":"Costa","sequence":"additional","affiliation":[{"name":"Psychology Institute, University of Brasilia, Brasilia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9723-6081","authenticated-orcid":false,"given":"Ana Lu\u00edsa dos Santos","family":"Pires","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and University Hospital, Medicine of the Child and Adolescent, University of Brasilia, Brasilia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1940-8690","authenticated-orcid":false,"given":"Elvio M","family":"Boato","sequence":"additional","affiliation":[{"name":"Center for Science and Technology, CogniAction Lab, Catholic University of Brasilia, Brasilia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,2,15]]},"reference":[{"key":"bibr1-17446295211050460","doi-asserted-by":"publisher","DOI":"10.15761\/COGRM.1000281"},{"key":"bibr2-17446295211050460","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055994"},{"key":"bibr3-17446295211050460","doi-asserted-by":"publisher","DOI":"10.1111\/apa.12101"},{"key":"bibr4-17446295211050460","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e3282f88bb4"},{"key":"bibr5-17446295211050460","doi-asserted-by":"publisher","DOI":"10.1038\/nrg.2016.154"},{"key":"bibr6-17446295211050460","doi-asserted-by":"publisher","DOI":"10.1097\/01.DBP.0000452240.39511.d4"},{"key":"bibr7-17446295211050460","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2010.01.012"},{"key":"bibr8-17446295211050460","doi-asserted-by":"publisher","DOI":"10.1515\/RNS.2011.037"},{"key":"bibr9-17446295211050460","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2016.04.026"},{"key":"bibr10-17446295211050460","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2006.05.021"},{"key":"bibr11-17446295211050460","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2012.66"},{"key":"bibr12-17446295211050460","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2019.01.012"},{"key":"bibr13-17446295211050460","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12376"},{"key":"bibr14-17446295211050460","doi-asserted-by":"publisher","DOI":"10.1097\/DBP.0000000000000646"},{"key":"bibr15-17446295211050460","unstructured":"Cambridge Cognition (2014) Simple reaction time (SRT) [Online]. 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