{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T02:30:10Z","timestamp":1777861810702,"version":"3.51.4"},"reference-count":53,"publisher":"SAGE Publications","issue":"1-2","license":[{"start":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T00:00:00Z","timestamp":1764028800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Research in Nursing"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Patients receiving parenteral nutrition (PN) are often thought to be at higher risk of catheter-related blood stream infections (CRBSIs) than patients receiving other infusions. Nursing practice in the administration of PN has focused on traditional aseptic\/sterile techniques using sterile gloves because of this perceived risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>To identify the evidence base for current aseptic practice in the administration of PN and association with incidence of CRBSI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A systematic review was conducted. MEDLINE, EMBASE, CINAHL Plus, and Cochrane Library databases were searched for studies reporting aseptic technique used\/taught in administration of PN.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Thirty-nine papers were identified. After title, abstract, and full text screening six studies were included. All studies were low-quality evidence, observational or quasi-experimental designs; no relevant controlled trials were identified. Evidence did not support the use of any one aseptic technique when administering PN. A structured approach to education and standardisation appeared to improve technique and reduce CRBSI. Use of sterile gloves versus non-sterile gloves did not appear to impact on CRBSI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>There is no evidence to support the use of aseptic\/sterile technique over other techniques in nurse administration of PN. However, there is a need for higher quality research in this area.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17449871251383615","type":"journal-article","created":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T13:26:06Z","timestamp":1764077166000},"page":"138-152","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Association of catheter-related blood stream infections and aseptic technique(s) used in administration of parenteral nutrition: a systematic review and narrative synthesis"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5033-8278","authenticated-orcid":false,"given":"Jane","family":"Fletcher","sequence":"first","affiliation":[{"name":"Consultant Nurse, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK"},{"name":"College of Medicine and Health, School of Nursing and Midwifery, University of Birmingham, Birmingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6505-8460","authenticated-orcid":false,"given":"Hardip","family":"Malhi","sequence":"additional","affiliation":[{"name":"Lead Nurse, University Hospitals Birmingham NHS Foundation Trust, Mindelsohn Way, Birmingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Topping","sequence":"additional","affiliation":[{"name":"Emeritus Professor, College of Medicine and Health, School of Nursing and Midwifery, University of Birmingham, Birmingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,11,25]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/emermed-2020-209567"},{"key":"e_1_3_3_3_1","volume-title":"Aseptic Non Touch Technique: The ANTT Clinical Practice Framework for all Invasive Clinical Procedures From Surgery to Community Care","author":"Association for Safe Aseptic Practice (ASAP)","year":"2015","unstructured":"Association for Safe Aseptic Practice (ASAP) (2015) Aseptic Non Touch Technique: The ANTT Clinical Practice Framework for all Invasive Clinical Procedures From Surgery to Community Care. 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