{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T08:17:57Z","timestamp":1783585077322,"version":"3.55.0"},"reference-count":47,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T00:00:00Z","timestamp":1783296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Research in Nursing"],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Early ambulation (EA) supports recovery in cardiovascular patients. Its effects on haemodynamic stability and clinical outcomes in non-ST elevation myocardial infarction (NSTEMI) patients before coronary angioplasty are unexplored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>To evaluate EA\u2019s impact on haemodynamic stability and clinical outcomes in NSTEMI patients before coronary angioplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      A quasi-experimental study was conducted in two cardiac wards with 154 NSTEMI patients, assigned to EA (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 77) or complete rest in bed (CRIB) (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 77). Haemodynamic parameters, telemetry events (non-sustained ventricular tachycardia) and cardiac events (angina, reinfarction, dyspnoea and syncope) were monitored. Logistic regression assessed associations between EA and clinical outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Demographic and clinical characteristics were similar between groups (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &gt; 0.05). Haemodynamic parameters remained stable in both groups (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &gt; 0.05). EA was associated with a 79% reduction in cardiac events (OR = 0.21, 95% confidence interval (CI) (0.07, 0.60),\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.003) and a trend towards fewer telemetry events (OR = 0.27, 95% CI (0.07, 1.03),\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.06). EA also shortened hospitalisation by a mean of 49.56 hours (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.02).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>EA before coronary angioplasty is safe, reduces cardiac events and shortens hospital stay. These findings support structured nursing-led EA as part of routine acute cardiology care and highlight its role in promoting patient-centred recovery, efficient resource utilisation and potential cost savings for healthcare providers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17449871261421460","type":"journal-article","created":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T05:57:53Z","timestamp":1783403873000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Early ambulation before percutaneous coronary intervention in patients with non-ST elevation myocardial infarction: a quasi-experimental study of haemodynamics and clinical outcomes"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8877-1632","authenticated-orcid":false,"given":"Jolyn Si Ying","family":"Chin","sequence":"first","affiliation":[{"name":"Assistant Nurse Clinician, Department of Cardiology, National University Health System, Singapore"},{"name":"Professor, Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choy Yee","family":"Lee","sequence":"additional","affiliation":[{"name":"Advanced Practice Nurse, Department of Cardiology, National University Health System, Singapore"},{"name":"Professor, Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tee Joo","family":"Yeo","sequence":"additional","affiliation":[{"name":"Senior Consultant, Assistant Professor, Department of Cardiology, National University Heart Centre, Singapore"},{"name":"Professor, Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poh Chi","family":"Tho","sequence":"additional","affiliation":[{"name":"Senior Nurse Researcher, Department of Nursing, National University Health System, Singapore"},{"name":"Professor, Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilson Wai San","family":"Tam","sequence":"additional","affiliation":[{"name":"Associate Professor, Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"},{"name":"Professor, Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenru","family":"Wang","sequence":"additional","affiliation":[{"name":"Professor, Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,6]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-023-04333-9"},{"key":"e_1_3_4_3_1","unstructured":"American College of Sports Medicine (2022) Guidelines for Exercise Testing and Prescription. 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