{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T12:29:07Z","timestamp":1793449747760,"version":"4.5.0"},"reference-count":47,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Child Health Research CIO","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Womens Health (Lond Engl)"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Turner syndrome (TS) is a rare sex chromosome aneuploidy, with an incidence of four in 10,000 new-born girls. TS is often associated with impaired social communication skills, but the extent to which these are attributable to Autism Spectrum Disorders (ASD) is uncertain. We made standardized assessments of the mental health and associated neurodevelopmental disorders in children and adolescents with TS and report on the prevalence of concurrent conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Our sample comprised 127 girls with TS, 5\u201319 years of age. We obtained reports of their mental health from a combination of diagnostic interview (the Development and Wellbeing Assessment (DAWBA)), from the Strengths and Difficulties Questionnaire (SDQ) and from the Social Responsiveness Scale (SRS-2). Sources of information included parents, teachers and self-reports. The prevalence of mental health disorders in this sample was compared with age\/sex matched national English data from typical controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Most individuals with TS (83%) had experienced significant social communication difficulties and nearly one in four (23%) met diagnostic criteria for ASD on the DAWBA. One-third (34%) had at least one mental health or neurodevelopmental condition, and those girls with an ASD were at a greater risk of a co-occurring emotional disorder and\/or attention deficit hyperactivity disorder (ADHD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Children and adolescents with TS are substantially more likely to meet criteria for ASD than their typically developing peers. Our finding has clinical implications for appropriate behavioural management from preschool through to adolescence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17455057221133635","type":"journal-article","created":{"date-parts":[[2022,12,6]],"date-time":"2022-12-06T04:38:43Z","timestamp":1670301523000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Mental health and neurodevelopment in children and adolescents with Turner syndrome"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6160-9731","authenticated-orcid":false,"given":"Jeanne","family":"Wolstencroft","sequence":"first","affiliation":[{"name":"The Great Ormond Street Institute of Child Health, University College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Mandy","sequence":"additional","affiliation":[{"name":"Division of Psychology and Language Sciences, University College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Skuse","sequence":"additional","affiliation":[{"name":"The Great Ormond Street Institute of Child Health, University College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,12,6]]},"reference":[{"key":"bibr1-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1017\/S0003480097006507"},{"key":"bibr2-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-17-0430"},{"key":"bibr3-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.31676"},{"key":"bibr4-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.23951"},{"key":"bibr5-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1111\/cch.12710"},{"key":"bibr6-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1080\/13554799908402746"},{"key":"bibr7-17455057221133635","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s11689-020-09334-1","volume":"13","author":"Bj\u00f6rlin Avdic H","year":"2021","journal-title":"J Neurodevelop Dis"},{"key":"bibr8-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1080\/09297049.2011.647900"},{"key":"bibr9-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1097\/DBP.0b013e3182255301"},{"key":"bibr10-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-021-04896-y"},{"key":"bibr11-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1007\/s13760-013-0264-9"},{"key":"bibr12-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1016\/j.chc.2007.02.004"},{"key":"bibr13-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(15)00277-1"},{"key":"bibr14-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-014-2265-9"},{"key":"bibr15-17455057221133635","doi-asserted-by":"publisher","DOI":"10.2147\/PRBM.S117499"},{"key":"bibr16-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1097\/00004703-200112000-00003"},{"key":"bibr17-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1080\/09513590400021227"},{"key":"bibr18-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsj106"},{"key":"bibr19-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2015.06.021"},{"key":"bibr20-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1515\/JPEM.2005.18.11.1111"},{"key":"bibr21-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1016\/1054-139X(95)00225-H"},{"key":"bibr22-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.12.1374"},{"key":"bibr23-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022230504787"},{"key":"bibr24-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2014.02.017"},{"key":"bibr25-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-200310000-00011"},{"key":"bibr26-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1037\/e557702010-001"},{"key":"bibr27-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1097\/chi.0b013e31803062bf"},{"key":"bibr28-17455057221133635","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.107.038729"},{"key":"bibr29-17455057221133635","unstructured":"Office for National Statistics. 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