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The current standard for ectopic pregnancy diagnosis includes ultrasound imaging and \u03b2-human chorionic gonadotropin (\u03b2-hCG) monitoring. In addition to \u03b2-hCG, serum markers are being explored as a potential for diagnosis, with activin-AB and pregnancy-associated plasma protein A specifically showing promise. Other diagnostic methods include endometrial sampling, with dilation and curettage showing the highest specificity; however, frozen section reduces the diagnostic timeline which may improve outcomes. Treatment options for confirmed ectopic pregnancies include medical, surgical, and expectant management. Chosen treatment methodology is based on \u03b2-hCG levels, hematologic stability, and risk of ectopic pregnancy rupture. Current innovations in ectopic pregnancy management aim to preserve fertility and include laparoscopic partial tubal resection with end-to-end anastomosis and uterine artery embolization with intrauterine infusion of methotrexate. Psychological interventions to improve patient mental health surrounding ectopic pregnancy diagnosis and treatment are also valuable innovations. This literature review aims to bring light to current ectopic pregnancy diagnostics, treatments, and future directions.<\/jats:p>","DOI":"10.1177\/17455057231160349","type":"journal-article","created":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T03:18:42Z","timestamp":1680232722000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":144,"title":["Overview of ectopic pregnancy diagnosis, management, and innovation"],"prefix":"10.1177","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6806-1032","authenticated-orcid":false,"given":"Kellie","family":"Mullany","sequence":"first","affiliation":[{"name":"Carle Illinois College of Medicine, University of Illinois Urbana Champaign, Urbana, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0983-1022","authenticated-orcid":false,"given":"Madeline","family":"Minneci","sequence":"additional","affiliation":[{"name":"Carle Illinois College of Medicine, University of Illinois Urbana Champaign, Urbana, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9558-1909","authenticated-orcid":false,"given":"Ryan","family":"Monjazeb","sequence":"additional","affiliation":[{"name":"Carle Illinois College of Medicine, University of Illinois Urbana Champaign, Urbana, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1322-5877","authenticated-orcid":false,"given":"Olivia","family":"C. 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