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Despite these alarming statistics, research on women\u2019s heart health remains underfunded and poorly prioritized, due in part to the historic exclusion of women from clinical trials and biomedical research. This editorial will highlight the scope of CVD in women, explore sex- and gender-specific risk factors such as gestational diabetes, early menopause, and psychosocial stress, and underscore barriers to quality care including implicit bias and structural inequities. It also calls for increased representation of women in clinical trials and medical fields. Policy and funding shifts are urgently needed to encourage sex-specific research and equitable healthcare delivery. This editorial concludes with a call to action for inclusive, interdisciplinary research approaches, that centers women and their unique biological realities. 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