{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T12:16:07Z","timestamp":1784204167089,"version":"3.55.0"},"reference-count":26,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Geneva University Hospitals - Commission des Affaires Humanitaires"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Womens Health (Lond Engl)"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Persistent infection with human papillomavirus is the prerequisite for the development of cervical precancerous and cancerous lesions. The aim of this study was to determine the time-to-viral clearance in a population of human papillomavirus\u2013infected Cameroonian women and to examine the possible predictors of viral persistence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      We conducted a prospective cohort study based on a population of human papillomavirus\u2013positive women having previously been recruited in a self-human papillomavirus-based cervical cancer screening campaign, who were invited for a control visit at 6 and 12\u2009months. We determined human papillomavirus clearance using self-sampling (Self-HPV) and physician-sampling (Dr-HPV), which were analyzed with a point-of-care assay (GeneXpert\n                      <jats:sup>\u00ae<\/jats:sup>\n                      IV; Cepheid, Sunnyvale, CA, USA). Logistic regression was performed to assess the relationship between sociodemographic and clinical characteristics with HPV clearance according to the two sampling techniques.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 187 participants were included in the study. At the 12\u2009months follow-up, 79.5% (n = 104) and 65.3% (n = 86) had cleared their human papillomavirus infection according to Dr-HPV and self-HPV, respectively (p = 0.001). Only parity (&gt;5 children) was statistically associated with viral persistence (p = 0.033). According to Dr-HPV, clearance of women treated with thermoablation at 12\u2009months was of 84.1% versus 70.2% for non-treated women (p = 0.075).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The human papillomavirus clearing rates found in our study are close to those found in other studies worldwide. Parity was significantly associated with human papillomavirus persistence. Larger, prospective studies are needed to confirm our results.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1745506518805642","type":"journal-article","created":{"date-parts":[[2018,12,19]],"date-time":"2018-12-19T07:36:24Z","timestamp":1545204984000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Clearance and persistence of the human papillomavirus infection among Cameroonian women"],"prefix":"10.1177","volume":"14","author":[{"given":"Mohamed","family":"Akaaboune","sequence":"first","affiliation":[{"name":"Gynecology Division, Department of Obstetrics and Gynecology, University Hospitals of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Kenfack","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Viviano","sequence":"additional","affiliation":[{"name":"Gynecology Division, Department of Obstetrics and Gynecology, University Hospitals of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliane","family":"Temogne","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Biomedical Sciences, Centre Hospitalier Universitaire (CHUY), Yaound\u00e9, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Catarino","sequence":"additional","affiliation":[{"name":"Gynecology Division, Department of Obstetrics and Gynecology, University Hospitals of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eveline","family":"Tincho","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Biomedical Sciences, Centre Hospitalier Universitaire (CHUY), Yaound\u00e9, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel","family":"Mbobda","sequence":"additional","affiliation":[{"name":"Protestant University, Bandjoun, Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phuong Lien","family":"Tran","sequence":"additional","affiliation":[{"name":"Gynecology Division, Department of Obstetrics and Gynecology, University Hospitals of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxane","family":"Camail","sequence":"additional","affiliation":[{"name":"Gynecology Division, Department of Obstetrics and Gynecology, University Hospitals of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Vassilakos","sequence":"additional","affiliation":[{"name":"Geneva Foundation for Medical Education and Research, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Petignat","sequence":"additional","affiliation":[{"name":"Gynecology Division, Department of Obstetrics and Gynecology, University Hospitals of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,10,24]]},"reference":[{"key":"bibr1-1745506518805642","volume-title":"GLOBOCAN 2012: estimated cancer incidence, mortality and prevalence worldwide in 2012, v1.0","author":"Ferlay J","year":"2012"},{"key":"bibr2-1745506518805642","unstructured":"World Health Organization. Guidelines for screening and treatment of precancerous lesions for cervical cancer prevention. Geneva: World Health Organization, 2013."},{"key":"bibr3-1745506518805642","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.07.047"},{"key":"bibr4-1745506518805642","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.27828"},{"key":"bibr5-1745506518805642","doi-asserted-by":"publisher","DOI":"10.5468\/ogs.2015.58.1.40"},{"key":"bibr6-1745506518805642","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2008.00567.x"},{"key":"bibr7-1745506518805642","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0b013e3181fb4547"},{"key":"bibr8-1745506518805642","unstructured":"Health nutrition population statistics: population estimates projections. 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