{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T05:47:34Z","timestamp":1780724854422,"version":"3.54.1"},"reference-count":8,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T00:00:00Z","timestamp":1468195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Stroke"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:p>We aimed to assess whether carotid siphon calcifications (as seen on computed tomography) are associated with worse performance in the Montreal Cognitive Assessment in 584 stroke-free individuals living in rural Ecuador. Using mean Montreal Cognitive Assessment score of subjects with Grade 1 calcifications (23.1\u2009\u00b1\u20094.2) as the referent category, fully adjusted generalized linear models showed significant associations between severity of carotid siphon calcifications and cognitive performance (mean Montreal Cognitive Assessment scores: 20.2\u2009\u00b1\u20094.8 for Grade 2 (p\u2009=\u20090.004), 19.7\u2009\u00b1\u20095.3 for Grade 3 (p\u2009=\u20090.0001), and 18.8\u2009\u00b1\u20094.1 for Grade 4 (p\u2009=\u20090.02)). Predictive Montreal Cognitive Assessment score margins were higher in individuals with Grade 1 calcifications than in other groups. This study shows an inverse relationship between calcium content in the carotid siphon and cognitive performance in Amerindians.<\/jats:p>","DOI":"10.1177\/1747493016660105","type":"journal-article","created":{"date-parts":[[2016,7,12]],"date-time":"2016-07-12T06:35:21Z","timestamp":1468305321000},"page":"935-937","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Calcifications in the carotid siphon inversely associate with cognitive performance in stroke-free community dwellers living in rural Ecuador (The Atahualpa Project)"],"prefix":"10.1177","volume":"11","author":[{"given":"Oscar H","family":"Del Brutto","sequence":"first","affiliation":[{"name":"School of Medicine, Universidad Esp\u00edritu Santo, Ecuador, Guayaquil, Ecuador"},{"name":"Department of Neurological Sciences, Hospital-Cl\u00ednica Kennedy, Guayaquil, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robertino M","family":"Mera","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren J","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Langone Medical Center, School of Medicine, New York University, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauricio","family":"Zambrano","sequence":"additional","affiliation":[{"name":"Community Center, The Atahualpa Project, Atahualpa, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan R","family":"King","sequence":"additional","affiliation":[{"name":"Langone Medical Center, School of Medicine, New York University, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,7,11]]},"reference":[{"key":"bibr1-1747493016660105","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61002-8"},{"key":"bibr2-1747493016660105","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2012.01.008"},{"key":"bibr3-1747493016660105","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2014.05.1758"},{"key":"bibr4-1747493016660105","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000001546"},{"key":"bibr5-1747493016660105","first-page":"495","volume":"20","author":"Woodcock RJ","year":"1999","journal-title":"AJNR Am J Neuroradiol"},{"key":"bibr6-1747493016660105","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53221.x"},{"key":"bibr7-1747493016660105","doi-asserted-by":"publisher","DOI":"10.1007\/s10900-014-9857-3"},{"key":"bibr8-1747493016660105","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.009716"}],"container-title":["International Journal of Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1747493016660105","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1747493016660105","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1747493016660105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:14:06Z","timestamp":1777706046000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1747493016660105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,11]]},"references-count":8,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.1177\/1747493016660105"],"URL":"https:\/\/doi.org\/10.1177\/1747493016660105","relation":{},"ISSN":["1747-4930","1747-4949"],"issn-type":[{"value":"1747-4930","type":"print"},{"value":"1747-4949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,11]]}}}