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VERSE is a PROBE trial designed to determine whether two types of intensive aphasia therapy, beginning within 14 days of acute stroke, provide greater therapeutic and cost-effectiveness than usual care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To publish the detailed statistical analysis plan for the VERSE trial prior to unblinding. This statistical analysis plan was based on the published and registered VERSE trial protocol and was developed by the blinded steering committee and management team, led by the trial statistician. This plan was developed using outcome measures and trial data collection forms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The VERSE statistical analysis plan is consistent with reporting standards for clinical trials and provides for clear and open reporting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Publication of a statistical analysis plan serves to reduce potential trial reporting bias and outlines transparent pre-specified analyses. Australian New Zealand Clinical Trials Registry (ANZCTR) Registration number: ACTRN12613000776707; Universal Trial Number (UTN) is U1111-1145-4130.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1747493018790055","type":"journal-article","created":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T06:46:05Z","timestamp":1538376365000},"page":"863-880","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Statistical analysis plan (SAP) for the Very Early Rehabilitation in Speech (VERSE) after stroke trial: an international 3-arm clinical trial to determine the effectiveness of early, intensive, prescribed, direct aphasia therapy"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7210-1295","authenticated-orcid":false,"given":"Erin","family":"Godecke","sequence":"first","affiliation":[{"name":"School of Medical and Health Science, Edith Cowan University, Joondalup, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tapan","family":"Rai","sequence":"additional","affiliation":[{"name":"School of Mathematical and Physical Sciences, University of Technology Sydney, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8162-682X","authenticated-orcid":false,"given":"Dominique A","family":"Cadilhac","sequence":"additional","affiliation":[{"name":"Stroke and Ageing Research, School of Clinical Science at Monash Health, Monash University, Melbourne, Australia"},{"name":"Centre of Research Excellence in Stroke Rehabilitation and Brain Recovery, Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Armstrong","sequence":"additional","affiliation":[{"name":"School of Medical and Health Science, Edith Cowan University, Joondalup, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandy","family":"Middleton","sequence":"additional","affiliation":[{"name":"Nursing Research Institute St Vincent's Health Australia, Sydney and Australian Catholic University, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Ciccone","sequence":"additional","affiliation":[{"name":"School of Medical and Health Science, Edith Cowan University, Joondalup, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Whitworth","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Curtin University, Perth, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miranda L","family":"Rose","sequence":"additional","affiliation":[{"name":"School of Allied Health, La Trobe University, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Holland","sequence":"additional","affiliation":[{"name":"Department of Speech, Language and Hearing Sciences, University of Arizona, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona","family":"Ellery","sequence":"additional","affiliation":[{"name":"Centre of Research Excellence in Stroke Rehabilitation and Brain Recovery, Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graeme J","family":"Hankey","sequence":"additional","affiliation":[{"name":"Medical School, The University of Western Australia, Perth, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2787-8484","authenticated-orcid":false,"given":"Julie","family":"Bernhardt","sequence":"additional","affiliation":[{"name":"Centre of Research Excellence in Stroke Rehabilitation and Brain Recovery, Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the VERSE Collaboration","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,10]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/1747493016641116"},{"key":"e_1_3_3_3_2","volume-title":"Western Aphasia Battery\u2013Revised","author":"Kertesz A","year":"2007","unstructured":"Kertesz A. 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