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From 1990 to 2019, the burden (in terms of the absolute number of cases) increased substantially (70.0% increase in incident strokes, 43.0% deaths from stroke, 102.0% prevalent strokes, and 143.0% DALYs), with the bulk of the global stroke burden (86.0% of deaths and 89.0% of DALYs) residing in lower-income and lower-middle-income countries (LMIC). This World Stroke Organisation (WSO) Global Stroke Fact Sheet 2022 provides the most updated information that can be used to inform communication with all internal and external stakeholders; all statistics have been reviewed and approved for use by the WSO Executive Committee as well as leaders from the Global Burden of Disease research group.<\/jats:p>","DOI":"10.1177\/17474930211065917","type":"journal-article","created":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T01:40:35Z","timestamp":1641433235000},"page":"18-29","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2914,"title":["World Stroke Organization (WSO): Global Stroke Fact Sheet 2022"],"prefix":"10.1177","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6372-1740","authenticated-orcid":false,"given":"Valery L","family":"Feigin","sequence":"first","affiliation":[{"name":"National Institute for Stroke and Applied Neurosciences, Auckland University of Technology, Auckland, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8363-4962","authenticated-orcid":false,"given":"Michael","family":"Brainin","sequence":"additional","affiliation":[{"name":"Clinical Neurology, Danube University Krems, Krems an der Donau, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Norrving","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Section of Neurology, Lund University, Sk\u00e5ne University Hospital, Lund, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila","family":"Martins","sequence":"additional","affiliation":[{"name":"Department of Neurology, Hospital de Cl\u00ednicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph L","family":"Sacco","sequence":"additional","affiliation":[{"name":"Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Werner","family":"Hacke","sequence":"additional","affiliation":[{"name":"Department of Neurology, Ruprecht-Karl-University Heidelberg, Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Fisher","sequence":"additional","affiliation":[{"name":"Neurology faculty at Beth Israel Deaconess Medical Center in Boston, Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0028-1968","authenticated-orcid":false,"given":"Jeyaraj","family":"Pandian","sequence":"additional","affiliation":[{"name":"Department of Neurology, Christian Medical College, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2584-8580","authenticated-orcid":false,"given":"Patrice","family":"Lindsay","sequence":"additional","affiliation":[{"name":"Heart and Stroke Foundation of Canada, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,1,5]]},"reference":[{"key":"bibr1-17474930211065917","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(21)00252-0"},{"key":"bibr2-17474930211065917","unstructured":"Owolabi MO, Thrift AG, Mahal A, et\u00a0al. 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