{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T22:46:18Z","timestamp":1788821178022,"version":"build-2803163510"},"reference-count":21,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T00:00:00Z","timestamp":1677715200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2020R1A2C3010304"],"award-info":[{"award-number":["NRF-2020R1A2C3010304"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019266","name":"Korea Medical Device Development Fund","doi-asserted-by":"publisher","award":["KMDF-RS-2022-00140478"],"award-info":[{"award-number":["KMDF-RS-2022-00140478"]}],"id":[{"id":"10.13039\/100019266","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Research Program funded by the Korean Disease Control and Prevention Agency","award":["2022-11-006"],"award-info":[{"award-number":["2022-11-006"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Stroke"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Although many studies about survival rates and functional outcomes after stroke have been published, studies on gender differences have reported conflicting results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>To determine whether there are differences in mortality and functional outcomes during the first 5\u2009years after a first-ever ischemic stroke in Korean males and females.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>This is an interim analysis of the Korean Stroke Cohort for Functioning and Rehabilitation, a prospective multicenter cohort study. Multifaceted functional assessments were performed repeatedly from 7\u2009days to 60\u2009months after stroke onset to test motor, ambulatory, cognitive, language, and swallowing functions as well as activities of daily living (ADLs) in patients with first-ever stroke. Of 10,636 first-ever-stroke patients admitted to nine representative hospitals in Korea, 8210 were ischemic stroke patients included in the mortality analysis. Among them, 6258 patients provided informed consent and 3508 completed functional assessments for 60\u2009months. Gender-related differences in 5-year mortality and functional recovery were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result:<\/jats:title>\n                    <jats:p>Women showed a significantly higher 5-year mortality rate than men after correction for possible covariates ( p\u2009 &lt;\u20090.05). In terms of functional outcomes, women showed worse ambulatory, cognitive, language, and ADL outcomes than men after adjusting for covariates (all p\u2009 &lt;\u20090.05). The 5-year recovery pattern differed significantly between genders only for ADL function (\u03b2-coefficient estimate\u2009=\u20090.34; p\u2009 =\u20090.03).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Five-year mortality rate, functional outcomes, and recovery patterns after first-ever ischemic stroke differed significantly by gender. These results suggest the need for gender-specific stroke care and long-term management strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17474930231159779","type":"journal-article","created":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T06:26:24Z","timestamp":1676355984000},"page":"839-846","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Gender differences in mortality and long-term functional outcomes after first-ever ischemic stroke: A prospective cohort study"],"prefix":"10.1177","volume":"18","author":[{"given":"Sang Moon","family":"Yun","sequence":"first","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Heart Vascular Stroke Institute, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7834-9494","authenticated-orcid":false,"given":"Seyoung","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Heart Vascular Stroke Institute, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Hyuk","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Heart Vascular Stroke Institute, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deog Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8718-0099","authenticated-orcid":false,"given":"Jongmin","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Konkuk University School of Medicine, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Kyun","family":"Sohn","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, College of Medicine, Chungnam National University, Daejeon, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Keun","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Chonnam National University Medical School, Gwangju, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Il","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang-Soo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Cheol","family":"Joo","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Wonkwang University School of Medicine, Iksan, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhee","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Statistics, Hallym University, Chuncheon, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeonghoon","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Health Convergence, Ewha Womans University, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyung-Jae","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Wonkwang University School of Medicine, Iksan, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6101-8851","authenticated-orcid":false,"given":"Yun-Hee","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Heart Vascular Stroke Institute, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, South Korea"},{"name":"Departments of Health Sciences and Technology, Medical Device Management & Research, Digital Health, SAIHST, Sungkyunkwan University, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,3,2]]},"reference":[{"key":"bibr1-17474930231159779","doi-asserted-by":"publisher","DOI":"10.5853\/jos.2013.15.1.2"},{"key":"bibr2-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1177\/17474930211065917"},{"key":"bibr3-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1177\/17474930221123175"},{"key":"bibr4-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.116.003436"},{"key":"bibr5-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.632547"},{"key":"bibr6-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.032850"},{"key":"bibr7-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1111\/ene.14299"},{"key":"bibr8-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000008615"},{"key":"bibr9-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-015-0293-5"},{"key":"bibr10-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-3182(09)70857-6"},{"key":"bibr11-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.517581"},{"key":"bibr12-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000068410.07397.D7"},{"key":"bibr13-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(08)70193-5"},{"key":"bibr14-17474930231159779","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2010.6.4.183"},{"key":"bibr15-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1298\/ptr.E10099"},{"key":"bibr16-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0209571"},{"key":"bibr17-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.016683"},{"key":"bibr18-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X18793324"},{"key":"bibr19-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.031659"},{"key":"bibr20-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1080\/00139157.2021.1898908"},{"key":"bibr21-17474930231159779","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-012-0230-5"}],"container-title":["International Journal of Stroke"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17474930231159779","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17474930231159779","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17474930231159779","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T07:21:46Z","timestamp":1777706506000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17474930231159779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,2]]},"references-count":21,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1177\/17474930231159779"],"URL":"https:\/\/doi.org\/10.1177\/17474930231159779","relation":{},"ISSN":["1747-4930","1747-4949"],"issn-type":[{"value":"1747-4930","type":"print"},{"value":"1747-4949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,2]]}}}