{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:30:53Z","timestamp":1777944653268,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T00:00:00Z","timestamp":1582588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Perioperative Practice"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:p>Perioperative tranexamic acid use is a popular choice among many surgeons for reducing surgical blood loss and its sequelae. While there is evidence in the literature that tranexamic acid use is effective in reducing blood loss in surgery for patients with hip fractures, there is less information on whether it leads to thromboembolic complications. We undertook a retrospective study in patients with hip fractures at two local hospitals to investigate if there was an increased risk of venous thromboembolism in patients who received tranexamic acid, and whether it reduced perioperative blood loss and the need for transfusion. We found that tranexamic acid used in patients undergoing hip fracture surgery reduced the drop in postoperative haemoglobin and the need for postoperative blood transfusion but was not associated with an increased risk of venous thromboembolism.<\/jats:p>","DOI":"10.1177\/1750458920905772","type":"journal-article","created":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T06:05:09Z","timestamp":1582610709000},"page":"378-382","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Does perioperative use of tranexamic acid in hip fracture patients increase the risk of venous thromboembolism and reduce the need for postoperative transfusions?"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7883-6364","authenticated-orcid":false,"given":"James","family":"Geddes","sequence":"first","affiliation":[{"name":"Royal Stoke University Hospital, Staffordshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3257-6253","authenticated-orcid":false,"given":"Greg","family":"McConaghie","sequence":"additional","affiliation":[{"name":"Princess Royal Hospital, NHS Trust, Telford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,2,25]]},"reference":[{"issue":"2","key":"bibr1-1750458920905772","volume":"9","author":"Basha J","year":"2005","journal-title":"The Internet Journal of Emergency and Intensive Care Medicine"},{"key":"bibr2-1750458920905772","unstructured":"British National Formulary [online] Available from: https:\/\/bnf.nice.org.uk\/medicinal-forms\/tranexamic-acid.html [Accessed November 2018]"},{"key":"bibr3-1750458920905772","first-page":"A34","volume":"23","author":"Conde Garcia MC","year":"2016","journal-title":"European Journal of Hospital Pharmacy"},{"key":"bibr4-1750458920905772","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.88B8.17534"},{"key":"bibr5-1750458920905772","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S174196"},{"key":"bibr6-1750458920905772","unstructured":"National Hip Fracture Database 2017 report [online] Available from: https:\/\/www.nhfd.co.uk\/files\/2017ReportFiles\/NHFD-AnnualReport2017.pdf [Accessed November 2018]"},{"key":"bibr7-1750458920905772","unstructured":"NICE Guideline [NG24]. Blood Transfusion Published date: November 2015 [online] Available from: https:\/\/www.nice.org.uk\/guidance\/ng24\/chapter\/Key-priorities-for-implementation#red-blood-cells [Accessed May 2019]"},{"issue":"5","key":"bibr8-1750458920905772","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.redar.2014.10.002","volume":"62","author":"Pinz\u00f3n-Florez CE","year":"2015","journal-title":"Revista Espa\u00f1ola de Anestesiolog\u00eda y Reanimaci\u00f3n"},{"key":"bibr9-1750458920905772","first-page":"437","volume":"45","author":"Sadeghi M","year":"2007","journal-title":"Acta Medica Iranica"},{"key":"bibr10-1750458920905772","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.93B1.24984"},{"key":"bibr11-1750458920905772","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-013-1761-2"}],"container-title":["Journal of Perioperative Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1750458920905772","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1750458920905772","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1750458920905772","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T08:02:57Z","timestamp":1777708977000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1750458920905772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,25]]},"references-count":11,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1177\/1750458920905772"],"URL":"https:\/\/doi.org\/10.1177\/1750458920905772","relation":{},"ISSN":["1750-4589","2515-7949"],"issn-type":[{"value":"1750-4589","type":"print"},{"value":"2515-7949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,25]]}}}