{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:32:02Z","timestamp":1777944722954,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T00:00:00Z","timestamp":1712102400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Perioperative Practice"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>This study investigated the effectiveness of intratracheal dexmedetomidine in reducing untoward laryngeal responses in paediatrics undergoing lower abdominal surgeries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This trial included 60 patients divided into two groups scheduled for lower abdominal surgeries. Group D were given intratracheal dexmedetomidine at a dosage of 0.5mg\/kg, while Group C received intratracheal saline (0.9%). The cough severity score, the Paediatric Objective Pain Scale for pain assessment, awareness, extubation, emergence agitation score, Ramsay sedation score and adverse effects were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>There was a significant difference in the incidence of coughing severity between Groups D and C both at extubation and after five minutes of extubation (p &lt; 0.001). The median scores of the Paediatric Objective Pain Scales and the median agitation scales of Group D were significantly lower over the first four hours (p &lt; 0.050). The mean time to first request rescue analgesia was significantly longer in the D group than in the control group (p &lt; 0.001). The mean total consumption of rescue analgesia in the first 24 hours postoperatively was significantly lower in the dexmedetomidine group (p &lt; 0.050). Awareness and extubation times were comparable in both groups, and none of the subjects reported any adverse effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In the current study, lower abdominal surgery patients who received intratracheal dexmedetomidine at a dose of 0.5mg\/kg 30 minutes before the completion of the procedure experienced smooth extubation and balanced anaesthetic recovery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17504589241231197","type":"journal-article","created":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T08:15:35Z","timestamp":1712132135000},"page":"249-257","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of intratracheal dexmedetomidine on recovery from general anaesthesia in paediatric patients undergoing lower abdominal surgeries: A randomised controlled trial"],"prefix":"10.1177","volume":"35","author":[{"given":"Marwa Mahmoud","family":"Abdel Rady","sequence":"first","affiliation":[{"name":"Anesthesia and Intensive Care Department, Faculty of Medicine, New Valley University, Kharga Oasis, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wesam Nashat","family":"Ali","sequence":"additional","affiliation":[{"name":"Anesthesia and Intensive Care Department, Faculty of Medicine, Assiut University, Assiut, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatma Batity","family":"Mansour","sequence":"additional","affiliation":[{"name":"Anesthesia and Intensive Care Department, Faculty of Medicine, Assiut University, Assiut, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekram","family":"Abdullah Othman","sequence":"additional","affiliation":[{"name":"Anesthesia and Intensive Care Department, Faculty of Medicine, Assiut University, Assiut, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghada Mohammad","family":"Abo Elfadl","sequence":"additional","affiliation":[{"name":"Anesthesia and Intensive Care Department, Faculty of Medicine, Assiut University, Assiut, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,4,3]]},"reference":[{"key":"e_1_3_2_2_1","article-title":"Attenuation of Haemodynamic parameters in response to pneumoperitoneum during laparoscopic cholecystectomy: A randomized controlled trial comparing infusions of propofol and dexmedetomidine","volume":"11","author":"Bhutia MP","year":"2017","unstructured":"Bhutia MP, Rai A 2017 Attenuation of Haemodynamic parameters in response to pneumoperitoneum during laparoscopic cholecystectomy: A randomized controlled trial comparing infusions of propofol and dexmedetomidine Journal of Clinical and Diagnostic Research 11 UC01\u2013UC04","journal-title":"Journal of Clinical and 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