{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:30:43Z","timestamp":1777944643644,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T00:00:00Z","timestamp":1723420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Perioperative Practice"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:p>Alkaptonuria is a rare autosomal recessive congenital disorder of metabolism that affects 1 in 250,000 live births. It manifests as ochronosis and degenerative arthritis due to the accumulation of homogentistic acid in cartilage and heart valves along with precipitation of renal, salivary, pancreatic and gall bladder calculi. It is noted to cause cardiac valve stenosis and regurgitation secondary to calcification leading to cardiac failure in 10% of patients. Through this report, we present a successful perioperative anaesthetic management of a 74-year-old man with cardiac ochronosis, who underwent an aortic valve replacement with coronary artery bypass graft surgery at our centre.<\/jats:p>","DOI":"10.1177\/17504589241268633","type":"journal-article","created":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T10:21:30Z","timestamp":1723458090000},"page":"163-166","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Perioperative anaesthetic management of an elderly high-risk male with cardiac ochronosis undergoing aortic valve replacement with coronary artery bypass graft: A case report"],"prefix":"10.1177","volume":"35","author":[{"given":"Nareshkumar","family":"Thiruvenkitasamy","sequence":"first","affiliation":[{"name":"National University Hospital Singapore, Singapore"},{"name":"Department of Cardiac Anaesthesiology, G. Kuppuswamy Naidu Memorial Hospital, Coimbatore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7130-7080","authenticated-orcid":false,"given":"Siddharth","family":"Manimozhi","sequence":"additional","affiliation":[{"name":"Department of Cardiac Anaesthesiology, G. Kuppuswamy Naidu Memorial Hospital, Coimbatore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,8,12]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0004563219879957"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezs043"},{"issue":"5","key":"e_1_3_2_4_1","first-page":"335","article-title":"Black heart at surgery \u2013 Primary diagnosis of alkaptonuria at surgery","volume":"9","author":"Karavaggelis A","year":"2017","unstructured":"Karavaggelis A, Young C, Attia R 2017 Black heart at surgery \u2013 Primary diagnosis of alkaptonuria at surgery Journal of Cardiolology and Current Research 9 (5) 335","journal-title":"Journal of Cardiolology and Current Research"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12055-020-01059-z"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9185.81839"},{"issue":"6","key":"e_1_3_2_7_1","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1007\/s10545-011-9339-z","article-title":"Cardiovascular manifestations of Alkaptonuria","volume":"34","author":"Pettit SJ","year":"2011","unstructured":"Pettit SJ, Fisher M, Gallagher JA, Ranganath LR 2011 Cardiovascular manifestations of Alkaptonuria Journal of Inherited Metabolic Disease: Official Journal of the Society for the Study of Inborn Errors of Metabolism 34 (6) 1177\u20131181","journal-title":"Journal of Inherited Metabolic Disease: Official Journal of the Society for the Study of Inborn Errors of Metabolism"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2012.12.015"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.4326\/jjcvs.48.107"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.5152\/eurjrheum.2018.18116"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.2147\/TACG.S186773"}],"container-title":["Journal of Perioperative Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17504589241268633","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17504589241268633","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17504589241268633","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T08:06:25Z","timestamp":1777709185000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17504589241268633"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,12]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1177\/17504589241268633"],"URL":"https:\/\/doi.org\/10.1177\/17504589241268633","relation":{},"ISSN":["1750-4589","2515-7949"],"issn-type":[{"value":"1750-4589","type":"print"},{"value":"2515-7949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,12]]}}}